Bibliometric analysis of publications on necroptosis from 2001 to 2021.
Bibliometric analysis of publications on necroptosis from 2001 to 2021.
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2001年至2021年坏死性凋亡出版物的文献计量分析
DOI：
10.3389/fcell.2022.946363
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发表时间：
2022
影响因子：
5.5
通讯作者：
Xie, Yong
中科院分区：
文献类型：
--
作者：
Liu, Yang;Zhou, Xiaojiang;Wang, Fangfei;Liu, Cong;Xie, Jun;Guan, Le;Xie, Yong
背景：坏死性凋亡在炎症、肿瘤和神经退行性疾病中起重要作用。近年来，与坏死性凋亡相关的研究越来越多，研究也日益深入。本研究旨在总结自2001年以来进行的研究，以发现该领域的热点和趋势。 方法：使用Web of Science Core数据库识别2001年至2021年关于坏死性凋亡的全球出版物。使用Rstudio、VOSviewer和CiteSpace进行文献计量学分析。 结果：从2001年到2021年，与坏死性凋亡相关的出版物数量逐渐增加。Vandenabeele P在45岁时发表的文章最多。袁继扬被引用次数最多，为5901次。坏死性下垂研究一直由中国和中国机构主导。《细胞死亡与疾病》在被检查的期刊中相关出版物的数量最多。在前10篇被引用最多的论文中，有7篇被引用次数超过500次。坏死性凋亡、细胞死亡、自噬、损伤、癌症、活化的B细胞核因子κ-轻链增强子和氧化应激是关键词分析中的重要关键词。最近的研究越来越多地集中在乳腺癌，受体相互作用的丝氨酸/苏氨酸蛋白激酶1，调节，假激酶混合谱系激酶结构域样蛋白，膜，保护和周期。 结论：对坏死性凋亡相关研究的兴趣继续稳步增加，各国和各机构在坏死性凋亡领域开展了密切合作。对坏死性凋亡相关分子和机制的研究以及坏死性凋亡与肿瘤的关系可能是今后研究的热点和方向。
Background: Necroptosis plays an important role in inflammation, cancer, and neurodegenerative diseases. In recent years, the number of studies related to necroptosis has increased and research has become increasingly in-depth. This study aimed to summarize the research conducted since 2001 to discover hotspots and trends in the field of necroptosis. Methods: The Web of Science Core database was used to identify global publications on necroptosis from 2001 to 2021. Bibliometric analysis was performed using Rstudio, VOSviewer, and CiteSpace. Results: The number of publications related to necroptosis gradually increased from 2001 to 2021. Vandenabeele P had the most publications at 45. Yuan JY had the most citations at 5,901. Necroptosis research has been dominated by China and Chinese institutions. Cell Death and Disease had the highest number of related publications among the examined journals. Seven of the top 10 most cited papers had more than 500 citations. Necroptosis, cell death, autophagy, injury, cancer, activated B cell nuclear factor kappa-light chain enhancer, and oxidative stress were important keywords in keyword analysis. Recent research has increasingly focused on breast cancer, receptor-interacting serine/threonine protein kinase 1, modulation, pseudokinase mixed lineage kinase domain-like protein, membrane, protection, and cycle. Conclusion: Interest in necroptosis-related research continues to increase steadily, and there is close cooperation between countries and institutions in the field of necroptosis. The study of necroptosis-related molecules and mechanisms, and the relationship between necroptosis and cancer, may be hotspots and directions in future research.
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