A smog chamber comparison of a microfluidic derivatisation measurement of gas-phase glyoxal and methylglyoxal with other analytical techniques
A smog chamber comparison of a microfluidic derivatisation measurement of gas-phase glyoxal and methylglyoxal with other analytical techniques
复制标题
气相乙二醛和甲基乙二醛的微流体衍生化测量与其他分析技术的烟雾室比较
DOI：
10.5194/amt-7-373-2014
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发表时间：
2014-01-01
影响因子：
3.8
通讯作者：
Munoz, A.
中科院分区：
文献类型：
--
作者：
Pang, X.;Lewis, A. C.;Munoz, A.
抽象。发展了一种微流控芯片实验室衍生化技术，用于测量气态乙二醛（GLY）和甲基乙二醛（MGLY）的十亿分之一（ppbV）混合比，并在烟雾室实验中与其他技术进行了比较。该方法使用邻-（2，3，4，5，6-五氟苄基）羟胺（PFBHA）作为衍生化试剂和微制造的平面玻璃微反应器，该微制造的平面玻璃微反应器包括入口、气体和流体分离和组合通道、混合接头和加热的毛细管反应微通道。增强的相接触面积与体积比和高传热速率的微反应器中导致快速和高效的衍生化反应，产生的流出物流准备直接引入到气相色谱-质谱仪（GC-MS）。当在最佳反应条件下衍生时，在0.7至400 ppbV的校准范围内观察到GLY的线性响应，并且在1.2至300 ppbV的MGLY的线性响应。方法的准确度（GLY为6.6%，MGLY为7.5%）、精密度（
Abstract. A microfluidic lab-on-a-chip derivatisation technique has been developed to measure part per billion (ppbV) mixing ratios of gaseous glyoxal (GLY) and methylglyoxal (MGLY), and the method is compared with other techniques in a smog chamber experiment. The method uses o-(2, 3, 4, 5, 6-pentafluorobenzyl) hydroxylamine (PFBHA) as a derivatisation reagent and a microfabricated planar glass micro-reactor comprising an inlet, gas and fluid splitting and combining channels, mixing junctions, and a heated capillary reaction microchannel. The enhanced phase contact area-to-volume ratio and the high heat transfer rate in the micro-reactor resulted in a fast and highly efficient derivatisation reaction, generating an effluent stream ready for direct introduction to a gas chromatograph-mass spectrometer (GC-MS). A linear response for GLY was observed over a calibration range 0.7 to 400 ppbV, and for MGLY of 1.2 to 300 ppbV, when derivatised under optimal reaction conditions. The analytical performance shows good accuracy (6.6% for GLY and 7.5% for MGLY), suitable precision (