Cervical cancer in the Republic of Panama.
Cervical cancer in the Republic of Panama.
复制标题
巴拿马共和国的宫颈癌。
DOI：
10.1093/oxfordjournals.aje.a113792
复制
发表时间：
1984
影响因子：
5
通讯作者：
C. Joplin
中科院分区：
文献类型：
--
作者：
W. Reeves;M. Brenes;R. C. Britton;Plinio F. Valdes;C. Joplin
宫颈癌在拉丁美洲比世界其他地方更常见。以前的工作表明，巴拿马也有很高的宫颈癌发病率，这种疾病集中在农村埃雷拉省;为了记录这一点并收集有关风险因素的详细信息，作者在巴拿马建立了一个以人口为基础的宫颈癌登记处。1974年至1979年诊断出的宫颈癌病例是通过访问该国每一家主要医院确定的。登记处从患者的医院病历中提取流行病学、临床和其他信息。1974年至1979年，按年龄调整的浸润性宫颈癌发病率为28.4/100，000;埃雷拉省农村地区的发病率最高（79.1/100，000），而巴拿马城市省的比率较低。（24.6/100，000）;原地病的模式类似（埃雷拉省为48.7/100，000，巴拿马省为17.6/100，000）。出生在埃雷拉省的妇女无论在诊断时居住在何处，宫颈癌发病率都很高（64.7/100 000），而巴拿马省的妇女发病率很低（12.4/100 000），与美国白人的发病率相当。除了癌症发病率高之外，埃雷拉省的妇女在非常年轻的时候就患上了侵袭性疾病; 35至39岁的妇女的发病率为151/100 000。
Cervical cancer is more common in Latin America than elsewhere in the world. Previous work indicated that Panama also had a high incidence of cervical cancer and that the disease clustered in rural Herrera Province; to document this and collect detailed information on risk factors, the authors established a population-based Cervical Cancer Registry in Panama. Cervical cancer cases diagnosed between 1974 and 1979 were identified by visiting every major hospital in the country. The registry abstracted epidemiologic, clinical, and other information from patients' hospital charts. It recorded an age-adjusted invasive cervical cancer incidence of 28.4/100,000 between 1974 and 1979; rural Herrera Province supported the highest rate (79.1/100,000), while urban Panama Province had a low rate (24.6/100,000); in situ disease followed a similar pattern (48.7/100,000 in Herrera Province and 17.6/100,000 in Panama Province). Women born in Herrera Province retained high cervical cancer rates irrespective of residence at diagnosis (64.7/100,000), while women from Panama Province had low rates (12.4/100,000) which were comparable to those seen in US whites. In addition to having high cancer rates, women from Herrera Province developed invasive disease at an unusually young age; women between 35 and 39 years of age had an incidence of 151/100,000.