Efficacy of HIV Prevention Interventions in Latin American and Caribbean Nations, 1995-2008: A Meta-Analysis
Efficacy of HIV Prevention Interventions in Latin American and Caribbean Nations, 1995-2008: A Meta-Analysis
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DOI：
10.1007/s10461-010-9763-3
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发表时间：
2010-12-01
影响因子：
4.4
通讯作者：
Johnson, Blair T.
中科院分区：
文献类型：
--
作者：
Huedo-Medina, Tania B.;Boynton, Marcy H.;Johnson, Blair T.
这项荟萃分析综合了37项艾滋病毒预防干预措施，这些研究是通过系统检索截至2009年1月可用的英文、西班牙文和葡萄牙文数据库获得的。干预措施大大增加了知识（d = 0.40）和使用避孕套（d = 0 25）但效果差异很大当干预措施集中在高危人群、分发避孕套时，会导致更多的避孕套使用，最合适的模型利用了与地理有关的因素，特别是国家人类发展指数和收入不平等指数（即，基尼指数）当人类发展指数和收入不平等较低时，提供至少3小时内容的干预措施取得了更好的成功，这表明，在需求最大的地方，密集的艾滋病毒预防活动取得了最大的成功，并讨论了拉丁美洲和加勒比地区艾滋病毒干预发展的影响。
This meta-analysis synthesized 37 HIV prevention interventions (from 28 studies) that were evaluated in Latin American and Caribbean nations These studies were obtained through systematic searches of English, Spanish, and Portuguese-language databases available as of January 2009 Overall, interventions significantly increased knowledge (d = 0 40) and condom use (d = 0 25) but the effects varied widely Interventions produced more condom use when they focused on high-risk individuals, distributed condoms, and explicitly addressed social-cultural components The best-fitting models utilized factors related to geography, especially indices of a nations' human development index (HDI) and income inequality (i e, Gini index) Interventions that provided at least 3 h of content succeeded better when HDI and income inequality were lower, suggesting that intensive HIV prevention activities succeed best where the need is greatest Implications for HIV intervention development in Latin America and the Caribbean are discussed