Breast cancer survivors at work
Breast cancer survivors at work
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DOI：
10.1097/jom.0b013e318165159e
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发表时间：
2008-07-01
影响因子：
3.2
通讯作者：
Olsen, Cara H.
中科院分区：
文献类型：
--
作者：
Hansen, Jennifer A.;Feuerstein, Michael;Olsen, Cara H.
导语：癌症幸存者可能会经历疲劳、认知障碍和情绪困扰等残留症状。这些症状可能会影响他们在工作中的能力。目前尚不清楚这些症状在多大程度上与职业活跃的乳腺癌幸存者的工作有关，乳腺癌幸存者是最常见的癌症幸存者群体。方法：100名有乳腺癌病史的兼职或全职工作的女性和103名非癌症对照组的样本完成了与身体疲劳、抑郁、焦虑和认知限制有关的问卷调查。人口统计变量、工作压力、工作类型、诊断阶段、治疗暴露和健康行为也被测量为潜在的混杂因素。结果：诊断后四年的乳腺癌幸存者报告年龄调整后的工作限制水平较高(F=32.708，P<；0.001)。疲劳组(β=-0.311，95%CI=-0.545~-0.076)和抑郁组(β=0.331，95%CI=0.024~0.638)之间存在显著的交互作用。在癌症幸存者组中，疲劳与工作限制的相关性更强，而在非癌症组中，抑郁症状与工作限制的相关性更强。虽然疲劳解释了模型中22%的方差，但它解释了症状负担对整体模型的71%的贡献。结论：在考虑了许多潜在的混杂因素后，乳腺癌存活者组的疲劳感与工作的相关性更强。迫切需要更好地了解和有效管理职业活跃的乳腺癌幸存者的工作场所疲劳。
Introduction: Residual symptoms such as fatigue, cognitive limitations, and emotional distress can be experienced by cancer survivors. These symptoms may impact their abilities at work. It is unclear to what degree these symptoms are associated with work in occupationally active breast cancer survivors, the most prevalent cancer survivor group. Methods: A sample of 100 women working part- or full-time with a history of breast cancer and a noncancer comparison group (n = 103) completed questionnaires related to physical fatigue, depression, anxiety, and cognitive limitations. Demographic variables, job stress, type of job, stage at diagnosis, treatment exposure, and health behaviors were also measured as Potential confounders. Results: Four years postdiagnosis breast cancer survivors reported higher levels of age-adjusted work limitations (F = 32.708, P < 0.001). Significant g-roup by fatigue (beta = -0.311, 95% CI = -0.545 to -0.076) and group by depression (beta = 0.331, 95% CI = 0.024 to 0.638) interactions were observed. Fatigue was more strongly related to work limitations in the cancer survivor g-roup whereas depressive symptoms were more strongly related to limitations at work in the noncancer group. Although fatigue accounted for 22% of the variance in the model, it explained 71% of the contribution of symptom burden to the overall model. Conclusions: Fatigue was more strongly related to work in the breast cancer survivor group after accounting for many Potential confounders. There is a pressing need to better understand and effectively manage fatigue in the workplace in occupationally active breast cancer survivors.