QUALITY-OF-LIFE OF PATIENTS WITH ULCERATIVE-COLITIS PREOPERATIVELY AND POSTOPERATIVELY

QUALITY-OF-LIFE OF PATIENTS WITH ULCERATIVE-COLITIS PREOPERATIVELY AND POSTOPERATIVELY
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DOI:
10.1016/0016-5085(91)90081-u
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发表时间:
1991-11-01
期刊:
影响因子:
29.4
通讯作者:
COHEN, Z
COHEN, Z
中科院分区:
医学1区
文献类型:
--
作者:
MCLEOD, RS;CHURCHILL, DN;COHEN, Z

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两种工具,时间权衡技术和直接询问目标,被用来分配需要手术的溃疡性结肠炎患者的感知生活质量的价值(效用)。效用从0到1,0表示死亡,1表示完全健康。对两组患者进行了研究。第一组20例,男14例,女6例;平均年龄(34.0±10.3)岁。使用时间权衡技术和直接询问目标的术前效用分别为0.58±0.34和0.38±0.27。术后平均效用显著增加,使用时间权衡技术时为0.98±0.07,使用直接询问目标时为0.88±0.19(P<0.05)。第二组包括93名至少在一年前做过手术的患者。28例采用传统回肠造口术,28例采用Kock袋,37例采用回肠储血袋。这三个亚组的平均效用在0.87±0.18到0.97±0.6之间。三个亚组间差异无统计学意义。这项研究表明,溃疡性结肠炎手术后生活质量得到改善,而且无论手术方式如何,生活质量都很高。
Two instruments, the time trade-off technique and direct questioning of objectives, were used to assign the worth (utility) of the perceived quality of life of patients who had ulcerative colitis requiring surgery. Utilities ranged from 0 to 1 with 0 signifying death and 1 signifying full health. Two groups of patients were studied. Group 1 consisted of 20 patients (14 male and 6 female; mean age, 34.0 ± 10.3 years) who were studied preoperatively and 1 year postoperatively. The mean preoperative utility was 0.58 ± 0.34 using the time trade-off technique and 0.38 ± 0.27 using the direct questioning of objectives. Mean utilities were significantly higher postoperatively, 0.98 ± 0.07 using the time trade-off technique and 0.88 ± 0.19 using the direct questioning of objectives (P< 0.05). Group 2 included 93 patients who had had surgery at least 1 year previously. Twenty-eight had conventional ileostomies, 28 had Kock pouches, and 37 had ileal reservoirs. Mean utilities for these three subgroups ranged from 0.87 ± 0.18 to 0.97 ± 0.6. No significant differences were detected among the three subgroups. This study suggests that quality of life is improved after surgery for ulcerative colitis and is high irrespective of the surgical procedure.