TRANSURETHRAL RESECTION OF THE PROSTATE AND BLADDER-TUMOR WITHOUT WITHDRAWAL OF WARFARIN THERAPY
TRANSURETHRAL RESECTION OF THE PROSTATE AND BLADDER-TUMOR WITHOUT WITHDRAWAL OF WARFARIN THERAPY
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DOI：
10.1111/j.1464-410x.1989.tb05322.x
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发表时间：
1989-12-01
期刊：
影响因子：
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通讯作者：
DESMOND, AD
中科院分区：
文献类型：
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作者：
PARR, NJ;LOH, CS;DESMOND, AD
在长期抗凝治疗且未停用华法林的患者中，进行了12例前列腺切除术和1例广泛膀胱肿瘤切除术。平均术前凝血酶原指数为2.3。4名患者需要输血。无严重并发症。监测手术和输注新鲜冰冻血浆（FFP）对抗凝水平的影响。FFP使凝血酶原指数降低0.2/单位。经尿道电切术可由经验丰富的泌尿科医生对华法林抗凝的患者安全进行，降低了与停用抗凝相关的严重血栓栓塞并发症的风险。
Twelve resections of prostate and 1 extensive bladder tumour were performed in patients on long-term anticoagulation without withdrawal of warfarin therapy. The mean preoperative prothrombin index was 2.3. Four patients required blood transfusion. There were no major complications. The effects of surgery and infusion of fresh frozen plasma (FFP) on the level of anticoagulation were monitored. FFP reduced the prothrombin index by 0.2/unit. Transurethral resection can be carried out safely by an experienced urologist on patients anticoagulated with warfarin, reducing the risk of serious thromboembolic complications associated with withdrawal of anticoagulation.