The Complexity of Fungal Vision
The Complexity of Fungal Vision
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DOI：
10.1128/microbiolspec.funk-0020-2016
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发表时间：
2016-12-01
影响因子：
3.7
通讯作者：
Corrochano, Luis M.
中科院分区：
文献类型：
--
作者：
Fischer, Reinhard;Aguirre, Jesus;Corrochano, Luis M.
正如我们所知，没有光，生命是不可能的。光不仅是主要的能量来源，也是许多生物体的重要信息来源。在进化过程中，只有少数几个感光系统能够感知光线。它们都是基于具有共轭双键的有机分子，该分子允许从可见光(或紫外光)到其同源蛋白质的能量转移，将主要的物理光反应转化为细胞生物行为。主要的三类受体是基于黄素的蓝光、基于视网膜的绿光(如视紫红质)和基于线性四吡咯的红光传感器。光不仅控制着可移动生物的行为，而且对包括真菌在内的许多固着微生物也很重要。在真菌中，光控制着发育决定和生理适应，以及生物钟。虽然在真菌中发现了所有主要类别的光感受器，但在分子水平上对信号过程的良好理解仅限于一些模式真菌。然而，目前的知识表明，光感知系统之间存在复杂的相互作用，远远超出了对光明和黑暗的简单感知。在这篇文章中，我们集中在几种真菌上的最新结果，这些结果表明光敏感和压力激活的丝裂原激活的蛋白激酶之间有很强的联系。
Life, as we know it, would not be possible without light. Light is not only a primary source of energy, but also an important source of information for many organisms. To sense light, only a few photoreceptor systems have developed during evolution. They are all based on an organic molecule with conjugated double bonds that allows energy transfer from visible (or UV) light to its cognate protein to translate the primary physical photoresponse to cell-biological actions. The three main classes of receptors are flavin-based blue-light, retinal-based green-light (such as rhodopsin), and linear tetrapyrrole-based red-light sensors. Light not only controls the behavior of motile organisms, but is also important for many sessile microorganisms including fungi. In fungi, light controls developmental decisions and physiological adaptations as well as the circadian clock. Although all major classes of photoreceptors are found in fungi, a good level of understanding of the signaling processes at the molecular level is limited to some model fungi. However, current knowledge suggests a complex interplay between light perception systems, which goes far beyond the simple sensing of light and dark. In this article we focus on recent results in several fungi, which suggest a strong link between light-sensing and stress-activated mitogen-activated protein kinases.