Global burden of asthma among children
Global burden of asthma among children
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DOI：
10.5588/ijtld.14.0170
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发表时间：
2014-11-01
影响因子：
4
通讯作者：
Pearce, N.
中科院分区：
文献类型：
--
作者：
Asher, I.;Pearce, N.
全球有3.34亿人患有哮喘，这个数字可能被低估了。它是儿童中最常见的慢性病。在全球残疾调整儿童寿命年排名中，哮喘是排名前20位的慢性疾病之一；在5-14岁的儿童中期，它是前10大原因之一。全球儿童哮喘死亡率为每100000人中有0.0%至0.7%。儿童哮喘症状(过去12个月出现喘息)的患病率在全球范围内存在显著差异，不同国家之间的差异高达13倍。虽然哮喘症状在许多高收入国家更为常见，但一些低收入和中等收入国家的哮喘症状患病率也很高。在过去12个月中，在患有喘息的儿童中，严重哮喘症状的发生率最高的是LMICs，而不是HICs。从1990年代到2000年代，哮喘症状在HIC的一些高发中心变得更加常见；在许多情况下，流行率保持不变，甚至下降。与此同时，许多人口众多的LMICs的患病率有所上升，这表明全世界的总体负担正在增加，因此全球哮喘患病率的差异正在缩小。据估计，哮喘的成本相对较高。全球儿童哮喘的负担，包括费用，需要使用标准化方法进行持续监测。
334 million people worldwide suffer from asthma, and this figure may be an underestimation. It is the most common chronic disease in children. Asthma is among the top 20 chronic conditions for global ranking of disability-adjusted life years in children; in the mid-childhood ages 5-14 years it is among the top 10 causes. Death rates from asthma in children globally range from 0.0 to 0.7 per 100000. There are striking global variations in the prevalence of asthma symptoms (wheeze in the past 12 months) in children, with up to 13-fold differences between countries. Although asthma symptoms are more common in many high-income countries (HICs), some low- and middle-income countries (LMICs) also have high levels of asthma symptom prevalence. The highest prevalence of symptoms of severe asthma among children with wheeze in the past 12 months is found in LMICs and not HICs. From the 1990s to the 2000s, asthma symptoms became more common in some high-prevalence centres in HICs; in many cases, the prevalence stayed the same or even decreased. At the same time, many LMICs with large populations showed increases in prevalence, suggesting that the overall world burden is increasing, and that therefore global disparities in asthma prevalence are decreasing. The costs of asthma, where they have been estimated, are relatively high. The global burden of asthma in children, including costs, needs ongoing monitoring using standardised methods.