A new piece in the kinetochore jigsaw puzzle.

A new piece in the kinetochore jigsaw puzzle.
复制标题

着丝粒拼图中的一个新部分。

DOI:
10.1083/jcb.201407048
复制
发表时间:
2014
期刊:
The Journal of cell biology
影响因子:
--
通讯作者:
Desai,Arshad
Desai,Arshad
中科院分区:
--
文献类型:
--
作者:
Corbett,KevinD;Desai,Arshad

文献摘要

相似文献

在真核细胞分裂中,着丝粒介导染色体附着到纺锤体微管上,并作为信号通路的支架,确保染色体分离的准确性。着丝粒的结构决定了它在有丝分裂中的作用。在本期中,Hornung et al.(2014.J.Cell Biol.http://dx.doi.org/201403081)在萌芽酵母中发现了动粒内部和外部区域之间的意想不到的联系,这为构建这种界面提出了一种新的模型。
In eukaryotic cell division, the kinetochore mediates chromosome attachment to spindle microtubules and acts as a scaffold for signaling pathways, ensuring the accuracy of chromosome segregation. The architecture of the kinetochore underlies its function in mitosis. In this issue, Hornung et al. (2014.J. Cell Biol.http://dx.doi.org/201403081) identify an unexpected linkage between the inner and outer regions of the kinetochore in budding yeast that suggests a new model for the construction of this interface.