A new piece in the kinetochore jigsaw puzzle.
A new piece in the kinetochore jigsaw puzzle.
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着丝粒拼图中的一个新部分。
DOI:
10.1083/jcb.201407048
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发表时间:
2014
期刊:
影响因子:
--
通讯作者:
Desai,Arshad
中科院分区:
文献类型:
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作者:
Corbett,KevinD;Desai,Arshad
In eukaryotic cell division, the kinetochore mediates chromosome attachment to spindle microtubules and acts as a scaffold for signaling pathways, ensuring the accuracy of chromosome segregation. The architecture of the kinetochore underlies its function in mitosis. In this issue, Hornung et al. (2014.J. Cell Biol.http://dx.doi.org/201403081) identify an unexpected linkage between the inner and outer regions of the kinetochore in budding yeast that suggests a new model for the construction of this interface.