Training-associated changes and stability of attention bias in youth: Implications for Attention Bias Modification Treatment for pediatric anxiety
Training-associated changes and stability of attention bias in youth: Implications for Attention Bias Modification Treatment for pediatric anxiety
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DOI：
10.1016/j.dcn.2012.11.001
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发表时间：
2013-04-01
影响因子：
4.7
通讯作者：
Pine, Daniel S.
中科院分区：
文献类型：
--
作者：
Britton, Jennifer C.;Bar-Haim, Yair;Pine, Daniel S.
注意力偏差修正疗法（ABMT）是一种新兴的焦虑症治疗方法，被认为可以修正潜在的、稳定的注意力模式。因此，ABMT研究应考虑注意偏向稳定性对注意训练反应的影响，尤其是在儿童人群中。ABMT研究通常依赖于点探测任务，其中个体在情绪中性刺激对之后检测探测。本研究提出了两个与ABMT和注意偏向稳定性相关的点探针实验。在实验1中，接受8周认知行为治疗（CBT）的焦虑青年被随机分配到ABMT组（n = 18）或安慰剂组（n = 18）。研究了另外两个对照组，仅接受CBT的焦虑青年（n = 17）和健康对照青年（n = 16）。积极的注意力训练对快乐的面孔并没有增加临床医生对CBT的反应;然而，接受训练的个人表现出减少自我报告的焦虑措施早于只接受CBT的个人。在实验2中，健康的青年（n = 12）完成了两次点探测任务，同时进行功能磁共振成像。类内相关表明，在腹外侧前额叶皮层和杏仁核的神经激活的稳定性，以响应注意力偏差。这两项研究共同探讨了注意力偏差稳定性可能影响ABMT未来工作的方式。(C)2012爱思唯尔有限公司保留所有权利。
Attention Bias Modification Treatment (ABMT), an emerging treatment for anxiety disorders, is thought to modify underlying, stable patterns of attention. Therefore, ABMT research should take into account the impact of attention bias stability on attention training response, especially in pediatric populations. ABMT research typically relies on the dot-probe task, where individuals detect a probe following an emotional-neutral stimulus pair. The current research presents two dot-probe experiments relevant to ABMT and attention-bias stability. In Experiment 1, anxious youth receiving 8-weeks of cognitive-behavioral therapy (CBT) were randomly assigned to ABMT that trains attention towards happy faces (n = 18) or placebo (n = 18). Two additional comparison groups, anxious youth receiving only CBT (n = 17) and healthy comparison youth (n = 16), were studied. Active attention training towards happy faces did not augment clinician-rated response to CBT; however, individuals receiving training exhibited reductions on self-report measures of anxiety earlier than individuals receiving CBT only. In Experiment 2, healthy youth (n = 12) completed a dot-probe task twice while undergoing functional magnetic resonance imaging. Intra-class correlation demonstrated stability of neural activation in response to attention bias in the ventrolateral prefrontal cortex and amygdala. Together, these two studies investigate the ways in which attention-bias stability may impact future work on ABMT. (C) 2012 Elsevier Ltd. All rights reserved.