ESTIMATING SAMPLE SIZES FOR BINARY, ORDERED CATEGORICAL, AND CONTINUOUS OUTCOMES IN 2 GROUP COMPARISONS
ESTIMATING SAMPLE SIZES FOR BINARY, ORDERED CATEGORICAL, AND CONTINUOUS OUTCOMES IN 2 GROUP COMPARISONS
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DOI：
10.1136/bmj.311.7013.1145
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发表时间：
1995-10-28
影响因子：
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通讯作者：
ALTMAN, DG
中科院分区：
文献类型：
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作者：
CAMPBELL, MJ;JULIOUS, SA;ALTMAN, DG
样本量计算现在对许多研究方案都是强制性的，但在常见情况下有用的方案并不都很容易获得。本文概述了两组研究中关于二元、有序分类和连续结果的样本量的计算方法。给出了计算公式和实例。最大功率通常是通过在两组中具有相等的数字来实现的。然而，这并不总是可能的，并给出了不相等的群体大小的计算。
Sample size calculations are now mandatory for many research protocols, but the ones useful in common situations are not all easily accessible. This paper outlines the ways of calculating sample sizes in two group studies for binary, ordered categorical, and continuous outcomes. Formulas and worked examples are given. Maximum power is usually achieved by having equal numbers in the two groups. However, this is not always possible and calculations for unequal group sizes are given.