Self-maintenance and self-reproduction in an abstract cell model.
Self-maintenance and self-reproduction in an abstract cell model.
复制标题
抽象细胞模型中的自我维护和自我繁殖。
DOI：
10.1006/jtbi.2000.2121
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发表时间：
2000
影响因子：
2
通讯作者：
T. Ikegami
中科院分区：
文献类型：
--
作者：
N. Ono;T. Ikegami
活细胞必须通过活跃的新陈代谢来维持其细胞膜。膜不是静态的，而是随着其内部反应而演变的动态结构。当我们反思原始细胞的出现和进化时，我们不应忘记细胞膜与细胞内代谢循环之间的相互依赖关系。在本文中，我们提出了一个简单的自我维护细胞抽象模型。代谢循环将产生自组装膜，该膜将包围代谢循环。我们证明自我维持细胞具有自发繁殖的潜力。此外，我们还展示了两种不同的细胞繁殖方式，具体取决于化学物质的流动性。在第一种情况下，细胞释放自催化化学物质，在母细胞外产生新细胞。在第二种情况下，细胞变得更大，并通过形成新的内部分裂膜将自身分裂成子细胞。
Living cells must maintain their membranes by active metabolism. The membrane is not static but a dynamic structure that has evolved along with its internal reactions. When we reflect on the emergence and evolution of primitive cells, we should not forget the mutual dependency between membranes and metabolic cycles inside the cell. In this paper, we present a simple abstract model of the self-maintaining cell. A metabolic cycle will produce a self-assembling membrane that will enclose the metabolic cycle. We show that a self-maintaining cell has the potential to reproduce itself spontaneously. Further, we have demonstrated two different ways of cellular reproduction depending on the mobility of chemicals. In the first case, a cell releases autocatalytic chemicals that create new cells outside the mother cell. In the second case, a cell grows larger and divides itself into daughter cells by creating a new internal dividing membrane.