Medullary inspiratory activity: influence of intercostal tendon organs and muscle spindle endings.

Medullary inspiratory activity: influence of intercostal tendon organs and muscle spindle endings.
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髓质吸气活动:肋间腱器官和肌梭末梢的影响。

DOI:
10.1152/jappl.1987.62.3.1046
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发表时间:
1987
期刊:
Journal of applied physiology (Bethesda, Md. : 1985)
影响因子:
--
通讯作者:
Shannon,R
Shannon,R
中科院分区:
--
文献类型:
--
作者:
Bolser,DC;Lindsey,BG;Shannon,R

文献摘要

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在去大脑和异戊巴比妥麻醉的猫中进行了研究,以确定肋间肌梭末梢(MSE)和腱器官(TO)对延髓吸气活动的影响。通过电刺激T6腹根的外周切割端引起的受阻碍的肌肉收缩被用于刺激没有MSE的外部和内部肋间TO。无论是外部或内部肋间肌肉收缩受阻减少膈和延髓吸气神经元的活动。振动用于选择性刺激外部或内部肋间MSE(分别为90和40微米振幅)。选择性刺激外部或内部肋间MSE不会改变膈神经或髓神经吸气神经元的活动。它的结论是,外部和内部肋间的TO有一个广泛的抑制作用,延髓吸气活动和肋间的MSE没有影响延髓吸气活动。
Studies were conducted to determine the effects of intercostal muscle spindle endings (MSEs) and tendon organs (TOs) on medullary inspiratory activity in decerebrate and allobarbital-anesthetized cats. Impeded muscle contractions, elicited by electrical stimulation of the peripheral cut end of the T6 ventral root, were used to stimulate external and internal intercostal TOs without MSEs. Impeded contractions of either the external or internal intercostal muscles reduced phrenic and medullary inspiratory neuronal activities. Vibration was used to selectively stimulate external or internal intercostal MSEs (90 and 40 micron amplitude, respectively). Selective stimulation of either external or internal intercostal MSEs did not change phrenic or medullary inspiratory neuronal activities. It is concluded that both external and internal intercostal TOs have a generalized inhibitory effect on medullary inspiratory activity and intercostal MSEs have no effect on medullary inspiratory activity.