Cytotoxicity of cyanoacrylate adhesives to cultured tendon cells
Cytotoxicity of cyanoacrylate adhesives to cultured tendon cells
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DOI：
10.1054/jhsb.1999.0279
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发表时间：
1999-12-01
期刊：
影响因子：
--
通讯作者：
Trail, IA
中科院分区：
文献类型：
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作者：
Evans, CE;Lees, GC;Trail, IA
使用人类肌腱细胞培养物测试了四种氰基丙烯酸酯粘合剂的体外细胞毒性。在长达 18 周的实验期间，所有四种粘合剂均被发现具有细胞毒性，即使浓度低至 1.7%。这项研究表明，目前状态下的此类粘合剂可能不适合重新连接切断的肌腱，因为它们的初始和长期毒性可能会阻碍肌腱的缓慢愈合过程。
The in vitro cytotoxicity of four cyanoacrylate adhesives,vas tested using cultures of cells derived from human tendons. All four mere found to be cytotoxic, even at concentrations as low as 1.7%, over the experimental period of up to 18 weeks, This study shows that such adhesives in their present state may not be suitable for re-joining cut tendons as their initial and long-term toxicity may hinder the slow healing process of tendons.