Epidemiologic study of insect allergy in children. II. Effect of accidental stings in allergic children.
Epidemiologic study of insect allergy in children. II. Effect of accidental stings in allergic children.
复制标题
儿童昆虫过敏的流行病学研究。
DOI：
10.1016/s0022-3476(83)80649-0
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Valentine,MD
中科院分区：
文献类型：
--
作者：
Schuberth,KC;Lichtenstein,LM;Kagey-Sobotka,A;Szklo,M;Kwiterovich,KA;Valentine,MD
One hundred eighty-one children with non-life-threatening reactions to insect stings and positive venom skin tests were randomized to treatment (53) or no-treatment (128) groups and followed up clinically and immunologically for at least two years to assess the results of accidental stings. Twenty-eight stings in 17 treated patients and 74 stings in 47 untreated children occurred, leading to one mild reaction in a treated patient, and eight in the no-treatment group (P=NS). No reaction was more serious than the original. Based on IgE antibody changes and skin test results, 87% of the untreated children were stung by insect to which they had clinical sensitivity by skin test. Vespid skin test sensitivity decreased 10-fold or more in both treated (72%) and untreated (44%) children. Of those with increased sensitivity. ≅ 70% had been stung. These data indicate that the incidence of sever reactions on resting is low in insect-allergic children, and that the majority show decreased skin test sensitivity over time.
