Features of childhood sexual abuse and the development of psychiatric and substance use disorders
Features of childhood sexual abuse and the development of psychiatric and substance use disorders
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DOI：
10.1192/bjp.179.5.444
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发表时间：
2001-11-01
影响因子：
10.5
通讯作者：
Kendler, KS
中科院分区：
文献类型：
--
作者：
Bulik, CM;Prescott, CA;Kendler, KS
研究背景儿童期性虐待（childhood sexual abuse，CSA）与儿童期精神障碍的发生有关，目的探讨儿童期性虐待与儿童期性虐待特征的相关性，以及儿童期性虐待与儿童期精神障碍的发生之间的关系。我们使用逻辑回归来探索CSA特征之间的关联，（由双胞胎和她的双胞胎姐妹报告）和终身重度抑郁症，广泛性焦虑症，神经性贪食症，结果在单变量和逐步多元回归分析中，预测因子的模式在不同的诊断中存在差异，尽管差异不显著。更大的风险与企图或完成性交，使用武力或威胁，虐待的亲属，和消极的反应，有人谁被告知虐待。观察到类似的模式。结论CSA的具体特征差异性地增加了以后精神病理学的风险;然而，CSA的特征和特定精神疾病的出现之间似乎没有独特的预测关系。资金详情见鸣谢。
Background Childhood sexual abuse (CSA) is associated with an increased risk of subsequent psychiatric disorders.Aims To explore the risk associated with features of CSA and examine whether specific associations exist between particular profiles of CSA and the development of specific syndromes.Method In a population-based sample of adult female twins, we used logistic regression to explore the association between features of CSA (reported by the twin and her co-twin) and lifetime major depression, generalised anxiety disorder, bulimia nervosa, panic disorder and alcohol and drug dependence.Results In univariate and stepwise multiple regressions, patterns of predictors differed, although not significantly, across diagnoses. Greater risk was associated with attempted or completed intercourse, the use of force or threats, abuse by a relative, and a negative response by someone who was told about the abuse. Similar patterns were observed with. co-twin reports.Conclusions Specific features of CSA differentially increase risk of later psychopathology; however, there do not appear to be unique predictive relationships between features of CSA and the emergence of specific psychiatric disorders.Declaration of interest None. Funding detailed in Acknowledgements.