Fluid Drop-Like Transition of Erythrocytes under Shear
Fluid Drop-Like Transition of Erythrocytes under Shear
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DOI：
10.1126/science.165.3890.288
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发表时间：
1969-07
期刊：
影响因子：
56.9
通讯作者：
H. Schmid-Sch�nbein;R. Wells
中科院分区：
文献类型：
--
作者：
H. Schmid-Sch�nbein;R. Wells
分散在高粘度连续介质中的红细胞具有液滴的流动特性。静止的细胞是双凹的，而在剪切作用下，它们逐渐变形成长椭球，它们的长轴平行于流动方向。血红细胞膜围绕着血红蛋白旋转，就像一个坦克的胎面。在高剪切速率下，这种机制大大降低了所有红细胞压积值下的粘度。
Red cells dispersed in a continuous medium of high viscosity possess the flow properties of fluid drops. The cells at rest are biconcave, while under shear they become progressively deformed into prolate ellipsoids, their long axis aligned parallel to the flow direction. The red cell membrane rotates around the hemoglobin like a tread of a tank. At high rates of shear this mechanism greatly reduces viscosity at all hematocrit values.