CORN-OIL AND MINERAL-OIL STIMULATE SHAM FEEDING IN RATS
CORN-OIL AND MINERAL-OIL STIMULATE SHAM FEEDING IN RATS
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DOI：
10.1016/0031-9384(90)90314-t
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发表时间：
1990-08-01
影响因子：
2.9
通讯作者：
GREENBERG, D
中科院分区：
文献类型：
--
作者：
MINDELL, S;SMITH, GP;GREENBERG, D
为了确定油对摄入的口觉影响，我们测量了在30分钟的假喂养期间，在整夜剥夺食物或非剥夺食物的大鼠中，1瓶玉米油和矿物油的摄入量。大鼠假喂食两种油。食物剥夺大鼠摄入显着更多的两种油比非剥夺大鼠。大鼠区分玉米油和矿物油，以及0.78%的玉米油乳剂和水。大鼠假饲8种稀释度玉米油时，摄入量与浓度呈倒U函数关系，12.5%、25%和50%玉米油乳剂的摄入量最大。尽管在1瓶测试中玉米油和矿物油的摄入量相似，有时相等，但在2瓶假喂养偏好测试中，食物剥夺大鼠对玉米油表现出强烈的偏好。介导油对摄入量和偏好的口腔效应的感觉机制尚不清楚，但嗅觉和三叉神经感觉系统是最有可能的候选者。需要进一步的工作来表征油的orosensory效应的效力，灵敏度和可辨别性，介导它们的机制，以及它们在控制脂肪摄入中的作用。
To determine the orosensory effects of oils on ingestion, we measured the 1-bottle intake of corn oil and of mineral oil during 30 minutes of sham feeding in rats that were food deprived overnight or nondeprived. Rats sham fed both oils. Food-deprived rats ingested significantly more of both oils than nondeprived rats. Rats discriminated corn oil from mineral oil and as little as 0.78% corn oil emulsion from water. When rats sham fed 8 dilutions of corn oil, intake was inverted-U function of concentration with maximal intakes produced by 12.5%, 25% and 50% corn oil emulsions. Despite similar, sometimes equal, intakes of corn oil and mineral oil in 1-bottle tests, food-deprived rats showed a strong preference for corn oil in 2-bottle, sham-feeding, preference tests. The sensory mechanisms that mediate the oral effects of oil on intake and a preference are not known, but the olfactory and trigeminal sensory systems are the most likely candidates. Further work is required to characterize the potency, sensitivity, and discriminability of the orosensory effects of oils, the mechanisms that mediate them, and their role in the control of fat intake.