THE INCIDENCE OF HERPES-ZOSTER
THE INCIDENCE OF HERPES-ZOSTER
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DOI：
10.1001/archinte.155.15.1605
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发表时间：
1995-08-07
影响因子：
--
通讯作者：
PLATT, R
中科院分区：
文献类型：
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作者：
DONAHUE, JG;CHOO, PW;PLATT, R
背景：很少有基于人群的带状疱疹自然史和流行病学研究。虽然相对常见的发病原因，特别是在老年人，当代估计疱疹测试仪的发病率是缺乏的。在此，我们描述了一个以人口为基础的调查，从1990年到1992年在一个健康维护organization.Methods：健康维护组织的自动化医疗记录包含临床和行政信息的护理提供给病人在门诊设置，急诊室，和医院的事件和复发性疱疹测试仪。通过医学筛查确定疱疹病毒试验者例。编码诊断记录。疱疹测试仪诊断代码的预测价值是通过回顾患者记录样本来确定的。所有潜在复发患者的记录也reviewed.Results：总发病率，基于1075例500 408人年，为215每100 000人年（95%置信区间，192至240每100 000），并没有因性别而异。虽然发病率随着年龄的增长而急剧上升，但大约5%的病例发生在15岁以下的儿童中。感染人类免疫缺陷病毒的记录在5%的人与事件疱疹测试仪和癌症的6%。四人确认复发的疱疹测试仪（744每10万人年，95%的置信区间，203至1907），这些人中有三人感染了人类免疫缺陷病毒。结论：记录的发病率疱疹测试仪是64%，高于30年前的报告，年龄标准化率是两倍以上。免疫抑制条件对总体发病率的影响很小，尽管它们与早期复发密切相关。
Background: There are few population-based studies of the natural history and epidemiology of herpes zoster. Although a relatively common cause of morbidity, especially among the elderly, contemporary estimates of herpes tester incidence are lacking. Herein we describe a population-based investigation of incident and recurrent herpes tester from 1990 through 1992 in a health maintenance organization.Methods: The health maintenance organization's automated medical records contain clinical and administrative information about care rendered to patients in ambulatory settings, emergency departments, and hospitals. Cases of herpes tester were ascertained by screening the medical. record for coded diagnoses. The predictive value of a herpes tester diagnosis code was determined by review of a sample of patient records. Records from all patients with potential recurrences were also reviewed.Results: The overall incidence, based on 1075 cases in 500 408 person-years, was 215 per 100 000 person-years (95% confidence interval, 192 to 240 per 100 000) and did not vary by gender. Although the rate increased sharply with age, approximately 5% of the cases occurred among children younger than 15 years. Infection with human immunodeficiency virus was documented in 5% of the persons with incident herpes tester and cancer in 6%. Four persons had confirmed recurrences of herpes tester (744 per 100 000 person-years; 95% confidence interval, 203 to 1907); three of these persons were infected with the human immunodeficiency virus.Conclusions: The recorded incidence of herpes tester was 64% higher than that reported 30 years ago; the age-standardized rate was more than twofold higher. Immunosuppressive conditions had little impact on overall incidence, although they were strongly associated with early recurrences.