Hypothermia After CPR Prolongs Conduction Times of Somatosensory Evoked Potentials
Hypothermia After CPR Prolongs Conduction Times of Somatosensory Evoked Potentials
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DOI：
10.1007/s12028-013-9856-8
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发表时间：
2013-08-01
影响因子：
3.5
通讯作者：
Horn, Janneke
中科院分区：
文献类型：
--
作者：
Bouwes, Aline;Doesborg, Patty G. G.;Horn, Janneke
为探讨亚低温对心肺复苏（CPR）后正中神经体感诱发电位（SEP）传导时间和波幅的影响，从前瞻性收集的数据库中选择CPR后接受亚低温治疗的患者，在亚低温期间和复温后记录SEP。测量N9（外周传导时间，PCT）、N13和N20的潜伏期和振幅。中枢传导时间（CCT）定义为峰-峰潜伏期N13-N20。由另一位观察者对25例患者的记录进行评估，以确定组内相关系数（ICC）。低温期间SEP的平均体温为33.1 A ℃（SD 0.8），复温后为37.1 A ℃（SD 0.8）。低温时N9、N13、N20的平均潜伏期和平均CCT较长。振幅无一致性差异。本研究表明，CPR后低温治疗时正中神经SEP的PCT和CCT较复温后延长。振幅并不一致。
To investigate the effect of mild hypothermia on conduction times and amplitudes of median nerve somatosensory evoked potentials (SEP) in patients after cardiopulmonary resuscitation (CPR).Patients treated with hypothermia after CPR who underwent SEP recording during hypothermia and after rewarming were selected from a prospectively collected database. Latencies and amplitudes of N9 (peripheral conduction time, PCT), N13, and N20 were measured. The central conduction time (CCT) was defined as peak-peak latency N13-N20. Recordings of 25 patients were assessed by a second observer to determine the intraclass correlation coefficient (ICC).A total of 115 patients were included. The mean body temperature at SEP during hypothermia was 33.1 A degrees C (SD 0.8) and after rewarming 37.1 A degrees C (SD 0.8). Mean latencies of N9, N13, and N20 and mean CCT were longer during hypothermia. There were no consistent differences in amplitudes. There was an almost perfect ICC for assessment of latencies and amplitudes.This study showed that PCT and CCT of median nerve SEP were prolonged during treatment with hypothermia after CPR compared with after rewarming. Amplitudes did not differ consistently.