Renal blood flow: measurement in vivo with rapid spiral MR imaging.

Renal blood flow: measurement in vivo with rapid spiral MR imaging.
复制标题

肾血流量:使用快速螺旋 MR 成像进行体内测量。

DOI:
10.1148/radiology.208.3.9722853
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发表时间:
1998
期刊:
Radiology.
影响因子:
--
通讯作者:
Pelc,N
Pelc,N
中科院分区:
--
文献类型:
--
作者:
Sommer,G;Corrigan,G;Fredrickson,J;Sawyer-Glover,A;Liao,JR;Myers,B;Pelc,N

文献摘要

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PURPOSETo assess the ability of three cine phase-contrast magnetic resonance (MR) imaging techniques to measure normal human renal blood flow (RBF) in vivo.MATERIALS AND METHODSEighteen healthy volunteers were studied with three cine phase-contrast MR imaging techniques: breath-hold, segmented k-space, two-dimensional, Fourier transform technique (ie, time-resolved imaging with automatic data segmentation, or TRIADS); a breath-hold rapid spiral acquisition; and a non-breath-hold rapid spiral acquisition that allowed resolution of both cardiac and respiratory cycles. In each case, total arterial RBF and blood flow per unit of renal volume were calculated. For each subject, RBF was measured with a standard technique of p-aminohippuric acid (PAH)-clearance hematocrit on the same day as the MR imaging examination was performed.RESULTSThe range of agreement (2 standard deviations, or 95% confidence interval) between RBF measurements obtained with the PAH-clearance hematocrit technique and the various cine phase-contrast techniques varied from +/- 17.6% to +/- 26.5%. The best agreement was obtained with non-breath-hold rapid spiral data, by using data from the end-expiratory phase of respiration.CONCLUSIONFindings with cine phase-contrast MR imaging employing rapid spiral acquisition are in good agreement with measurements made with PAH-clearance hematocrit and give the promise of clinical measurements of RBF.