Nickel oxide hollow rnicrosphere for non-enzyme glucose detection
Nickel oxide hollow rnicrosphere for non-enzyme glucose detection
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DOI：
10.1016/j.bios.2013.11.006
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发表时间：
2014-04-15
影响因子：
12.6
通讯作者：
Chen, Junhong
中科院分区：
文献类型：
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作者：
Ci, Suqin;Huang, Taizhong;Chen, Junhong
以十二烷基硫酸钠（SDS）为辅助剂，乙醇和水为溶剂，采用溶剂热法制备了氧化镍空心微球（NiO-HMS）。采用透射电子显微镜（TEM）、扫描电子显微镜（SEM）和粉末X射线衍射（XRD）等技术对样品的形貌和结构进行了表征。结果表明，产物具有由多孔纳米片骨架相互连接而成的中空微球结构。电化学研究表明，NiO-HMS具有良好的稳定性和较高的催化活性，可用于无酶电流型葡萄糖传感器中。结果表明，该传感器具有线性响应范围宽（1.67 μ M-6.87 mM）、响应时间短（3 s）、检测下限低（0.53 μ M）、灵敏度高（与2.39 mA mM（-1）cm（-2）相近）、稳定性和重复性好等优点。(C)2013爱思唯尔有限公司版权所有。
A facile strategy has been developed to fabricate nickel oxide hollow microspheres (NiO-HMSs) through a solvothermal method by using a mixed solvent of ethanol and water with the assistance of sodium dodecyl sulfate (SDS). Various techniques, including transmission electron microscopy (TEM), scanning electron microscopy (SEM), and powder X-ray diffraction (XRD), were used to characterize the morphology and the structure of as-prepared samples. It was confirmed that the products possess a hollow microsphere structure that is constructed by interconnecting porous nanoplate framework. Electrochemical studies indicate that the NiO-HMS exhibits excellent stability and high catalytic activity for electrocatalytic oxidation of glucose in alkaline solutions, which enables the NiO-HMS to be used in enzyme-free amperometric sensors for glucose determination. It was demonstrated that the NiO-HMS-based glucose biosensor offers a variety of merits, such as a wide linear response window for glucose concentrations of 1.67 mu M-6.87 mM, short response time (3 s), a lower detection limit of 0.53 mu M (S/N=3), high sensitivity (similar to 2.39 mA mM(-1) cm(-2)) as well as good stability and repeatability. (C) 2013 Elsevier B.V. All rights reserved.