Neuronal GDPGP1 and glycogen metabolism: friend or foe?

Neuronal GDPGP1 and glycogen metabolism: friend or foe?
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神经元 GDPGP1 和糖原代谢:朋友还是敌人?

DOI:
10.1083/jcb.202001006
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发表时间:
2020
期刊:
The Journal of cell biology
影响因子:
--
通讯作者:
Ma,DengkeK
Ma,DengkeK
中科院分区:
--
文献类型:
--
作者:
Singhal,NeelS;Lee,EvanM;Ma,DengkeK

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成人大脑消耗葡萄糖用于能量需求,并将葡萄糖主要作为糖原储存在星形胶质细胞中。Schulz等人(2020. J. Cell Biol. https://doi.org/10.1083/jcb.201807127)鉴定了可能通过小鼠和C.线虫神经元
The adult brain consumes glucose for energy needs and stores glucose as glycogen mainly in astrocytes. Schulz et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201807127) identify the stress-regulated metabolic enzyme GDPGP1 that promotes neuronal survival likely through glycogen reserves in mouse and C. elegans neurons.