ULTRASONOGRAPHICAL ASSESSMENT OF MORBIDITY IN SCHISTOSOMIASIS-MANSONI IN MADAGASCAR - A COMMUNITY-BASED STUDY IN A RURAL-POPULATION
ULTRASONOGRAPHICAL ASSESSMENT OF MORBIDITY IN SCHISTOSOMIASIS-MANSONI IN MADAGASCAR - A COMMUNITY-BASED STUDY IN A RURAL-POPULATION
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DOI：
10.1016/0035-9203(95)90498-0
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发表时间：
1995-03-01
影响因子：
2.2
通讯作者：
ESTERRE, P
中科院分区：
文献类型：
--
作者：
BOISIER, P;SERIEYE, J;ESTERRE, P
1993年6月至11月，在马达加斯加中西部曼氏血吸虫流行的一个村庄的全体居民中进行了寄生虫学、临床和超声波调查。S.在接受检查的544人中，61.8%的人的粪便中发现了曼氏虫卵; 15-19岁年龄组的感染率最高（85.7%）。感染最严重的是10-14岁年龄组，其中几何平均卵数为265个卵/g粪便，34.3%的人排泄超过400个卵/g。卵子数量从15岁开始稳步下降。对482名2岁以上的居民进行了超声检查：根据S分期建议，其中29%的人出现了明确的可疑的相关河流改变。世界卫生组织开罗工作组提出的曼索尼感染。在30岁以下的受试者中从未观察到3期。这与在严重病变发生之前需要长期感染是一致的。仅在20-29岁年龄组中发现卵子计数与肝脏改变程度之间存在显著关系。
Between June and November 1993, a parasitological, clinical and ultrasonographical survey was carried out in the mid west of Madagascar, among the whole population of a village where Schistosoma mansoni was endemic. S. mansoni eggs were found in the stools of 61.8% of the 544 individuals examined; the highest prevalence of infection (85.7%) was observed in the 15-19 years old age group. The most intense infections were recorded in the 10-14 years age group, in which the geometric mean egg count was 265 eggs/g of faeces and 34.3% of the individuals excreted more than 400 eggs/g. The egg count decreased steadily from the age of 15 years. Ultrasonographical examination was performed in 482 inhabitants older than 2 years: 29% of them presented definite schistosome associated river alterations according to the proposals for staging S. mansoni infection made by the World Health Organization Cairo working group. Stage 3 was never observed in subjects under 30 years old. This is consistent with the need for a long-standing infection before serious lesions occur. A significant relationship between egg count and degree of liver alterations was found only in the 20-29 years age group.