DIAGNOSIS OF SMALL HEPATOCELLULAR-CARCINOMA - CORRELATION OF MR IMAGING AND TUMOR HISTOLOGIC-STUDIES
DIAGNOSIS OF SMALL HEPATOCELLULAR-CARCINOMA - CORRELATION OF MR IMAGING AND TUMOR HISTOLOGIC-STUDIES
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DOI：
10.1148/radiology.159.2.3008213
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发表时间：
1986-05-01
期刊：
影响因子：
19.7
通讯作者：
TATENO, Y
中科院分区：
文献类型：
--
作者：
EBARA, M;OHTO, M;TATENO, Y
对43例较小的肝细胞癌(HC)和36例其他肝脏占位性病变的患者进行了肝脏磁共振(MR)研究。在27例肝细胞癌患者中，有组织学检查结果。所有CT可在没有造影剂的情况下发现的局灶性病变，通过MR成像以更高的对比度来描绘。肿瘤的检出与肿瘤大小有关，最长轴为97.5%，最长轴为2 cm，最长轴为33.3%。MRI显示包裹性肝细胞癌环形征的频率是CT扫描的两倍。反转恢复(IR)图像比T2加权自旋回波图像更好地描述了肝细胞癌的内部结构。病变分为四种类型：低信号、等信号、高信号和混合信号。后三者为肝细胞癌的相对特征，与癌组织脂肪变性密切相关。肝纤维化患者的T1值往往较长；脂肪变性患者的T1值较短。T1和T2松弛时间有助于鉴别诊断。
Magnetic resonance (MR) images of the liver were used to study 43 patients with relatively small hepatocellular carcinomas (HCCs) and 36 with other hepatic mass lesions. In 27 HCC patients, histologic findings were available. All focal lesions detectable by CT without contrast media were delineated with greater contrast by MR imaging. The rate of detection depended on tumor size, being 97.5% fpr HCCs > 2 cm in the longest axis and 33.3% for those < 2 cm. MR imaging demonstrated the ring sign characteristic of encapsulated HCC twice as frequently as CT scans. Inversion recovery (IR) images depicted the internal structure of the HCC better than T2-weighted spin-echo images. Lesions were classified into four patterns of intensity: low, iso, high, and mixed. The latter three were relatively characteristic of HCC and related closely with steatosis of cancer tissue. HCCs with fibrosis tended to have long T1 values; those with steatosis has short T1 values. T1 and T2 relaxation times were useful in the differential diagnosis.