Detection of Brachytherapy Seeds Using 3-D Transrectal Ultrasound
Detection of Brachytherapy Seeds Using 3-D Transrectal Ultrasound
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DOI：
10.1109/tbme.2010.2053926
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发表时间：
2010-10-01
影响因子：
4.6
通讯作者：
Lawrence, Peter D.
中科院分区：
文献类型：
--
作者：
Wen, Xu;Salcudean, Septimiu (Tim) E.;Lawrence, Peter D.
近距离放射治疗种子的检测在前列腺近距离放射治疗的剂量学中起着关键作用。然而，使用B型经直肠超声(TRUS)进行粒子定位仍然是前列腺近距离放射治疗的一个挑战，主要是由于B型经直肠超声图像质量相对较低，近距离放射治疗的粒子尺寸较小。在本文中，我们提出了一种利用三维超声进行近距离放射治疗种子检测的新方案。三维反射功率图像是从超声射频信号计算出来的，而不是传统的B型图像。然后，植入的种子在由先验知识(例如，针入口点和种子放置)确定的3-D局部搜索空间中被分割。针插入轨迹也可以通过霍夫变换进行局部检测。实验结果表明，所提出的解决方案很好地在根据实际治疗计划植入的前列腺体模中进行种子定位，该治疗计划包括来自26个针头的136个种子。
Detection of brachytherapy seeds plays a key role in dosimetry for prostate brachytherapy. However, seed localization using B-mode transrectal ultrasound (TRUS) still remains a challenge for prostate brachytherapy, mainly due to the small size of brachytherapy seeds in the relatively low-quality B-mode TRUS images. In this paper, we propose a new solution for brachytherapy seed detection using 3-D ultrasound. A 3-D reflected power image is computed from ultrasound RF signals, instead of conventional B-mode images. Then, implanted seeds are segmented in 3-D local search spaces that are determined by a priori knowledge, e.g., needle entry points and seed placements. Needle insertion tracks are also detected locally by the Hough transform. Experimental results show that the proposed solution works well for seed localization in a prostate phantom implanted according to a realistic treatment plan with 136 seeds from 26 needles.