Hepatitis E

Hepatitis E
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DOI:
10.1016/s0140-6736(11)61849-7
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发表时间:
2012-06-30
期刊:
影响因子:
168.9
通讯作者:
Dalton, Harry R.
Dalton, Harry R.
中科院分区:
医学1区
文献类型:
--
作者:
Kamar, Nassim;Bendall, Richard;Dalton, Harry R.

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戊型肝炎病毒(HEV)是在20世纪80年代苏联占领阿富汗期间发现的,当时一个军营爆发了不明原因的肝炎。研究小组的一名成员摄入了受影响士兵的粪便提取液。他生病了,电子显微镜在他的粪便中发现了这种新病毒(名为HEV)。随后,在许多资源贫乏的国家发现了地方性HEV。在全球范围内,HEV是急性病毒性肝炎最常见的原因。这种病毒最初被认为不是在发达国家发生的,但最近的报告表明这种想法是错误的。本次研讨会的目的是描述有关HEV的最新发现,以及它们如何改变我们对其对全球人类健康影响的理解。
Hepatitis E virus (HEV) was discovered during the Soviet occupation of Afghanistan in the 1980s, after an outbreak of unexplained hepatitis at a military camp. A pooled faecal extract from affected soldiers was ingested by a member of the research team. He became sick, and the new virus (named HEV), was detected in his stool by electron microscopy. Subsequently, endemic HEV has been identified in many resource-poor countries. Globally, HEV is the most common cause of acute viral hepatitis. The virus was not initially thought to occur in developed countries, but recent reports have shown this notion to be mistaken. The aim of this Seminar is to describe recent discoveries regarding HEV, and how they have changed our understanding of its effect on human health worldwide.