Reactive extraction of lactic acid using alamine 336 in MIBK: equilibria and kinetics
Reactive extraction of lactic acid using alamine 336 in MIBK: equilibria and kinetics
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DOI：
10.1016/s0168-1656(02)00057-3
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发表时间：
2002-07-17
影响因子：
4.1
通讯作者：
Pangarkar, VG
中科院分区：
文献类型：
--
作者：
Wasewar, KL;Heesink, ABM;Pangarkar, VG
乳酸是一种重要的商业产品，从水溶液中提取乳酸是基于发酵的工业和废物流回收的日益增长的需求。胺萃取工艺的设计需要所用酸-胺（溶剂）系统的 (i) 平衡和 (ii) 动力学数据。已确定在作为稀释剂的甲基异丁基酮 (MIBK) 中用 Alamine 336 萃取乳酸的平衡。有机相（胺+MIBK）可负载乳酸的程度表示为负载比，z=[HL](o)/[B](i,o)。基于反应萃取的化学计量和所涉及的平衡的计算表明，转移到有机相的乳酸比从反应的（1:1）化学计量中预期的要多。萃取平衡被解释为化学计量为 1:1 和 2:1 的两种酸-胺物质连续形成的结果。已经估计了 (1:1) 和 (2:1) 的平衡络合常数。还测定了 MIBK 中的 Alamine 336 提取乳酸的动力学。在此类研究中，首次利用伴随化学反应的萃取理论来获得 MIBK 中的 Alamine 336 萃取乳酸的动力学。在搅拌池中，乳酸和 MIBK 中的丙胺 336 之间的反应属于方案 3，萃取伴随着扩散膜中发生的快速化学反应。已发现该反应在丙胺 336 中为零级反应，在乳酸中为一级反应，速率常数为 1.38 s(-1)。这些数据将有助于设计提取过程。 (C) 2002 Elsevier Science B.V. 保留所有权利。
Lactic acid is an important commercial product and extracting it out of aqueous solution is a growing requirement in fermentation based industries and recovery from waste streams. The design of an amine extraction process requires (i) equilibrium and (ii) kinetic data for the acid-amine (solvent) system used. Equilibria for lactic acid extraction by alamine 336 in methyl-iso-butyl-ketone (MIBK) as a diluent have been determined. The extent to which the organic phase (amine + MIBK) may be loaded with lactic acid is expressed as a loading ratio, z = [HL](o)/[B](i,o). Calculations based on the stoichiometry of the reactive extraction and the equilibria involved indicated that more lactic acid is transferred to the organic phase than would be expected from the (1:1) stoichiometry of the reaction. The extraction equilibrium was interpreted as a result of consecutive formation of two acid-amine species with stoichiometries of 1:1 and 2: 1. Equilibrium complexation constant for (1: 1) and (2: 1) has been estimated. Kinetics of extraction of lactic acid by alamine 336 in MIBK has also been determined. In a first study of its kind, the theory of extraction accompanied by a chemical reaction has been used to obtain the kinetics of extraction of lactic acid by alamine 336 in MIBK. The reaction between lactic acid and alamine 336 in MIBK in a stirred cell falls in Regime 3, extraction accompanied by a fast chemical reaction occurring in the diffusion film. The reaction has been found to be zero order in alamine 336 and first order in lactic acid with a rate constant of 1.38 s(-1). These data will be useful in the design of extraction processes. (C) 2002 Elsevier Science B.V. All rights reserved.