The PedsQL™:: Measurement model for the pediatric quality of life inventory
The PedsQL™:: Measurement model for the pediatric quality of life inventory
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DOI：
10.1097/00005650-199902000-00003
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发表时间：
1999-02-01
期刊：
影响因子：
3
通讯作者：
Rode, CA
中科院分区：
文献类型：
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作者：
Varni, JW;Seid, M;Rode, CA
背景儿科患者的健康相关生活质量（HRQOL）的自我报告已成为一个重要的基于患者的健康结果。一个实用的，有效的通用措施HRQOL有利于评估风险，跟踪健康状况，并衡量治疗效果的儿科人群。PedsQL是一种简单、标准化、通用的评估工具，使用儿科癌症作为示例模型，系统评估患有慢性健康状况的儿科患者的患者和父母对HRQOL的看法。PedsQL基于测量HRQOL的模块化方法，由15项全球HRQOL核心指标和8个评估特定症状或治疗领域的补充模块组成。PedsQL是根据经验从291名儿童癌症患者及其父母在不同治疗阶段收集的数据得出的。信度和效度都进行了测定。核心指标的Cronbach α系数（患者α = .83，父母α = .86）可用于组间比较。患者自我报告模块的α值通常在0.70至0.89之间。判别或临床有效性，使用已知组的方法，证明了患者的治疗与停止治疗。这11个量表显示出小到中等的正相关，支持多维测量模型。进一步的结构效度通过多方法-多特质矩阵使用标准化的心理社会量表进行了证明。结果支持PedsQL作为HRQOL的可靠和有效的措施。PedsQL核心和模块化设计使其足够灵活，可用于儿科慢性健康状况的各种研究和临床应用。
BACKGROUND. Pediatric patients' self-report of health-related quality of life (HRQOL) has emerged as an important patient-based health outcome. A practical, validated generic measure of HRQOL facilitates assessing risk, tracking health status, and measuring treatment outcomes in pediatric populations.METHODS. The PedsQL is a brief, standardized, generic assessment instrument that systematically assesses patients' and parents' perceptions of HRQOL in pediatric patients with chronic health conditions using pediatric cancer as an exemplary model. The PedsQL is based on a modular approach to measuring HRQOL and consists of a 15-item core measure of global HRQOL and eight supplemental modules assessing specific symptom or treatment domains. The PedsQL was empirically derived from data collected from 291 pediatric cancer patients and their parents at various stages of treatment.RESULTS. Both reliability and validity were determined. Cronbach's alpha coefficients for the core measure (alpha = .83 for patient and alpha = .86 for parent) were acceptable for group comparisons. Alphas for the patient self-report modules generally ranged from .70 to .89. Discriminant or clinical validity, using the known-groups approach, was demonstrated for patients on- versus off-treatments. The 11 scales showed small-to-medium positive intercorrelations, supporting the multidimensional measurement model. Further construct validity was demonstrated via a multimethod-multitrait matrix using standardized psychosocial questionnaires.CONCLUSION. The results support the PedsQL as a reliable and valid measure of HRQOL. The PedsQL core and modular design makes it flexible enough to be used in a variety of research and clinical applications for pediatric chronic health conditions.