INNERVATION OF NONMYSTACIAL VIBRISSAE IN THE ADULT-RAT
INNERVATION OF NONMYSTACIAL VIBRISSAE IN THE ADULT-RAT
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DOI：
10.1002/cne.903570402
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发表时间：
1995-07-10
影响因子：
2.5
通讯作者：
RICE, FL
中科院分区：
文献类型：
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作者：
FUNDIN, BT;ARVIDSSON, J;RICE, FL
啮齿类动物囊垫的振动滤泡窦复合体（F-SCs）受不同类型的感觉神经末梢的神经支配。在神秘的F-SCs中，有一个部位，内圆锥形体（ICB），只有在那些有节奏地摇动它们的神秘触须的物种中，如大鼠，才有独特的神经支配。在这项研究中，我们检查了大鼠非神秘性F-SCs的神经支配。眶上、眶后、颈外侧、颈正中、颏下和腕前肢的F-SCs在低温恒温器上切割，制备用于抗人蛋白基因产物（PGP 9.5）免疫荧光或使用Winkelmann银染色技术。非囊性F-SCs的大部分神经支配与囊性F-SCs相似。Ah由一条大的深振动神经（DVN）和几条较小的浅振动神经（svn）支配。与在结缔组织垫中一样，svn表现出默克尔神经末梢和自由神经末梢的分布，其性质与所有非结缔组织F-SCs的网状脊领相似，并向icb提供周向末梢，但正中颈和腕部F-SCs除外。不仅颈中部和腕部F-SCs的ICB神经支配相对稀疏，而且腕部的ICB神经支配也有很大一部分从dvn上升而来，而dvn在其他部位的ICB贡献很小。与神秘性垫层F-SCs类似，dvn提供环形窦水平的默克尔和披针形末梢，以及海绵窦水平的网状和不规则披针形末梢。然而，除了眶后的F-SCs外，所有的F-SCs都有相对较少的披针形末梢。腕骨F-SCs也有相对较少的环窦默克尔末梢，弥漫性分布，仅限于外根鞘的浅表部分。海绵窦内也缺乏网状和不规则的针状末梢。然而，腕F-SCs在ICB、环窦和海绵窦中有一组独特的微粒末梢，这在其他F-SCs中很少见。PGP 9.5免疫荧光还在ICB和环窦水平显示了两组精细的轮廓，这在以前的神秘性F-SCs中未见过。虽然ICB神经的分布与触须运动之间没有相关性，但F-SC神经分布的区域差异提示触须在身体不同部位可能存在功能差异。(C) 1995 Wiley-Liss, Inc。
Vibrissal follicle-sinus complexes (F-SCs) in the mystacial pad of rodents are heavily innervated by different types of sensory nerve endings. One site in mystacial F-SCs, the inner conical body (ICB), is uniquely well innervated only in those species, such as the rat, that rhythmically whisk their mystacial vibrissae. In this study, we examined the innervation of rat nonmystacial F-SCs, which are not whisked. Supraorbital, posteroorbital, lateral cervical, median cervical, submental, and carpal forelimb F-SCs were cut on a cryostat and were either prepared for anti-human protein gene product (PGP 9.5) immunofluorescence or stained using the Winkelmann silver technique. Much of the innervation of the nonmystacial F-SCs is similar to that of mystacial F-SCs. Ah are innervated by a large deep vibrissal nerve (DVN) and several smaller superficial vibrissal nerves (SVNs). As in the mystacial pad, the SVNs show a distribution of Merkel and free nerve endings qualitatively similar to the rete ridge collar of all the nonmystacial F-SCs as well as provide circumferentially oriented endings to the ICBs to all but median-cervical and carpal F-SCs. Not only was the ICB innervation relatively sparse in median-cervical and carpal F-SCs, but a large portion of the carpal ICB innervation also ascended from the DVNs, which make only a small ICB contribution in other locations. Similar to mystacial pad F-SCs, the DVNs provided Merkel and lanceolate endings to the level of the ring sinus as well as reticular and irregular lanceolate-like endings to the level of the cavernous sinus. However, all but the posteroorbital F-SCs have relatively few lanceolate endings. Carpal F-SCs also have relatively few ring-sinus Merkel endings, which are diffusely distributed, are limited to the superficial portion of the outer root sheath. They also lack reticular and irregular lanceolate-like endings in the cavernous sinus. However, carpal F-SCs have a unique set of corpuscular endings in the ICB, ring sinus, and cavernous sinus that are rarely seen in other F-SCs. PGP 9.5 immunofluorescence also revealed two sets of fine-caliber profiles at the level of the ICB and ring sinus that were not previously seen in mystacial F-SCs. Although there was no correlation between ICB innervation and whisking, the regional variations in F-SC innervation suggest that functional differences may exist between vibrissae at different locations in the body. (C) 1995 Wiley-Liss, Inc.