[A case of cardiovascular Behçet's disease detected as multiple nodular shadows on chest X-ray].
[A case of cardiovascular Behçet's disease detected as multiple nodular shadows on chest X-ray].
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[胸部X线检查发现多发结节性阴影的心血管白塞氏病一例]。
DOI：
10.11389/jjrs1963.35.1074
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
M. Fujita
中科院分区：
文献类型：
--
作者：
H. Yoshimura;J. Ishii;N. Watanabe;A. Aida;K. Miyamoto;Y. Kawakami;M. Fujita
报告1例心血管behaperet病。一名30岁男子因发高烧入住我院。胸部x线显示多发结节影。超声心动图显示右心室有附壁血栓。诊断多发性肺脓毒性栓塞，并给予抗生素治疗。附壁血栓很快消失，但随后在同一部位复发。入院后第90天。手术切除了附壁血栓。组织学上，血栓由大量中性粒细胞和纤维蛋白组成。对血栓附着的心内膜的检查显示非特异性炎症，伴有纤维化改变和坏死肉芽。心血管behet病的诊断基于以下发现：口腔溃疡、针状结节、血栓性静脉炎、双侧葡萄膜炎和HLA-B51阳性。经类固醇激素和环孢素治疗后，血栓完全溶解，炎症症状减轻。虽然心血管behaperet病的各种临床和病理特征已被报道，但壁上血栓产生多发性肺脓毒性栓塞是罕见的。
A case of cardiovascular Behçet's disease is reported. A 30-year-old man was admitted to our hospital with a high fever. Multiple nodular shadows were revealed on chest X-ray. Echocardiography revealed a mural thrombus in the right ventricle. A diagnosis of multiple pulmonary septic embolisms was made, and antibiotics were administered. The mural thrombus soon resolved, but later recurred in the same location. On the 90th day after admission. The mural thrombus was surgically removed. Histologically, the thrombus consisted of numerous neutrophils and fibrin. Examination of the endocardium attached to the thrombus revealed nonspecific inflammation, with fibrotic change and necrosing granulation present. A diagnosis of cardiovascular Behçet's disease was made based on the following findings: oral ulcerations, acneiform nodules, thrombophlebitis, bilateral uveitis, and positive HLA-B51. After treatment with steroid hormones and cyclosporine, the thrombus resolved completely, and inflammatory signs diminished. Though various clinical and pathological characteristics of cardiovascular Behçet's disease have been reported, it is rare for a mural thrombus to produce multiple pulmonary septic embolisms.