Trichomonas vaginalis and Human Immunodeficiency Virus Coinfection Among Women Under Community Supervision: A Call for Expanded T. vaginalis Screening.

Trichomonas vaginalis and Human Immunodeficiency Virus Coinfection Among Women Under Community Supervision: A Call for Expanded T. vaginalis Screening.
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DOI:
10.1097/olq.0000000000000503
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发表时间:
2016-10
影响因子:
3.1
通讯作者:
El-Bassel N
El-Bassel N
中科院分区:
医学4区
文献类型:
--
作者:
Davis A;Dasgupta A;Goddard-Eckrich D;El-Bassel N

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美国有大量的社区监督人口,其中越来越多的是妇女。阴道毛滴虫感染与艾滋病毒感染和传播的风险增加密切相关,特别是在妇女中,但对艾滋病毒和T。在社区监督下的妇女中存在阴道混合感染。本文研究了T.迷走神经感染和T.纽约市社区监督下的妇女基线时的阴道炎和艾滋病毒合并感染。它还检查了12个月的结果,妇女治疗T。流浪汉妇女接受了艾滋病毒和T的生物检测。基线和12个月随访时的迷走神经功能。在333名接受性传播感染检测的妇女中,77名妇女(23.1%)T检测呈阳性。44例(13.3%)为HIV阳性。HIV阳性妇女的T。与HIV阴性女性相比,女性的迷走神经感染率为36.4%,而HIV阴性女性为21.3%,p≤0.05。16名女性(4.8%)同时感染了T.阴道炎和艾滋病在T.基线时有58例(75.3%)迷走神经感染,接受了医疗保健提供者的治疗。在接受治疗的患者中,17例(29.3%)T检测呈阳性。12个月随访时的迷走神经。鉴于T.在这一样本的妇女中,特别是在HIV阳性的妇女中,有高水平的再感染或持续感染,筛查T。在社区监督下,妇女的流浪可能对减少这一高危人群中艾滋病毒的感染和传播产生重大影响。一项对社区监督下的妇女的研究发现,T。艾滋病毒阳性妇女的阴道感染率高于艾滋病毒阴性妇女。
The United States has a large community supervision population, a growing number of whom are women. Trichomonas vaginalis infection is strongly associated with an increased risk of HIV acquisition and transmission, particularly among women, but there is a paucity of research on HIV and T. vaginalis co-infection among women under community supervision. This paper examines the prevalence of T. vaginalis infection and T. vaginalis and HIV co-infection at baseline among women under community supervision in New York City. It also examines the 12-month outcomes of women treated for T. vaginalis. Women received biological tests for HIV and T. vaginalis at baseline and 12 months follow-up. Of the 333 women tested for sexually transmitted infections, 77 women (23.1%) tested positive for T. vaginalis at baseline and 44 (13.3%) were HIV positive. HIV-positive women had significantly higher rates of T. vaginalis infection than HIV-negative women (36.4% vs. 21.3%, p≤0.05). Sixteen women (4.8%) were co-infected with T. vaginalis and HIV. Of the 77 women who were positive for T. vaginalis infection at baseline, 58 (75.3%) received treatment by a healthcare provider. Of those who received treatment, 17 (29.3%) tested positive for T. vaginalis at the 12 month follow-up. Given the high prevalence of T. vaginalis among this sample of women, particularly among HIV positive women, and high levels of reinfection or persistent infection, screening for T. vaginalis among women under community supervision may have a substantial impact on reducing HIV acquisition and transmission among this high risk population. A study of women under community supervision found higher rates of T. vaginalis infection among HIV-positive women than among HIV-negative women.