Risk stratification and outcome of cellulitis admitted to hospital
Risk stratification and outcome of cellulitis admitted to hospital
复制标题
DOI：
10.1016/j.jinf.2010.03.014
复制
发表时间：
2010-06-01
影响因子：
28.2
通讯作者：
Miyakis, S.
中科院分区：
文献类型：
--
作者：
Figtree, M.;Konecny, P.;Miyakis, S.
目的：方法：回顾性分析1999年1月至2006年12月在某三级医院住院的395例蜂窝组织炎/丹毒患者的临床资料，分析其死亡率和不良预后的危险因素。并发症112例（28.4%）。中位住院时间为5天。与死亡率、不良结局和住院时间延长（>7天）独立相关的因素是菌血症和白蛋白60、症状持续时间>4天、低白蛋白血症、菌血症、MRSA分离和有效抗生素时间>8小时。MRSA在2003-2006年住院患者中更常见（OR 2.43，95% CI：1-12-5.27）。菌血症以链球菌为主（11/20）。传染病医生输入独立相关较短的hospitalis.Conclusions：蜂窝织炎/丹毒需要住院治疗赋予相当大的发病率和死亡率。入院时存在的临床标志物可用于对患者死亡率和不良结局的风险进行分层。(C)2010年英国感染学会。由爱思唯尔有限公司出版。保留所有权利。
Objectives: To identify risk factors associated with mortality and adverse outcome of community acquired cellulitis/erysipelas requiring hospital admission.Methods: A retrospective analysis of 395 episodes of cellulitis/erysipelas admitted to a tertiary referral hospital between January 1999 and December 2006.Results: Mortality was 2.5% (10/395). There were 112 complications (28.4%). Median hospitalisation was 5 days. Factors independently associated with mortality, adverse outcome and prolonged stay (>7 days) were bacteraemia and albumin 60, symptom duration >4 days, hypoalbuminaemia, bacteraemia, isolation of MRSA and time to effective antibiotics >8 h. MRSA was more frequent among patients admitted during 2003-2006 (OR 2.43, 95% CI: 1-12-5.27). Streptococci accounted for most bacteraemia (11/20). Infectious Disease physician input was independently associated with shorter hospitalisation.Conclusions: Cellulitis/erysipelas requiring hospitalisation confers considerable morbidity and mortality. Clinical markers present on admission can be used to stratify patient risk of mortality and adverse outcome. (C) 2010 The British Infection Society. Published by Elsevier Ltd. All rights reserved.