Ring-closing metathesis: A facile construct for alkaloid synthesis
Ring-closing metathesis: A facile construct for alkaloid synthesis
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DOI：
10.1351/pac200577071207
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发表时间：
2005-07-01
影响因子：
1.8
通讯作者：
Martin, SF
中科院分区：
文献类型：
--
作者：
Martin, SF
已发现闭环复分解是用于合成官能化的桥接氮杂环的高度有效的反应。该方法的实用性已经在几个案例研究中建立，包括一个简单的合成托烷环系统和有效的，对映选择性合成的天然产物（-）-peduncularine和（+）-anatoxin-a。
Ring-closing metathesis has been found to be a highly effective reaction for the synthesis of functionalized, bridged nitrogen heterocycles. The utility of the process has been established in several case studies, including a facile synthesis of the tropane ring system and efficient, enantioselective syntheses of the natural products (-)-peduncularine and (+)-anatoxin-a.