Left Inferior Frontal Gyrus Integrates Multisensory Information in Category Learning
Left Inferior Frontal Gyrus Integrates Multisensory Information in Category Learning
复制标题
左额下回在类别学习中整合多感官信息
DOI：
10.1093/cercor/bhaa029
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发表时间：
2020-08-01
期刊：
影响因子：
3.7
通讯作者：
Mo, Lei
中科院分区：
文献类型：
--
作者：
Li, You;Seger, Carol;Mo, Lei
人类能够通过轻松且快速地整合来自听觉和视觉等多感官信息，对在世界中遇到的事物（例如猫）进行分类。然而，大脑如何学习多感官类别仍不明确。本研究首次利用功能性磁共振成像来探究支撑多感官信息整合（II）类别学习的神经机制。无论信息来自单一感官还是多种感官，一个感官模态通用网络都会参与II分类，该网络包括左侧脑岛、右侧额下回（IFG）、辅助运动区、左侧中央前回、双侧顶叶皮层以及右侧尾状核和苍白球。在正确分类时，壳核的活动比错误分类时更为活跃。关键的是，左侧额下回以及左侧尾状核的体部和尾部在多感官II分类中被激活，而在单感官II分类中未被激活，这表明该网络在类别学习过程中对整合多感官信息发挥着特定作用。本研究结果将我们对左侧额下回在多感官处理中作用的理解，从语言领域扩展到了视听学习这一更广泛的范畴。
Humans are able to categorize things they encounter in the world (e.g., a cat) by integrating multisensory information from the auditory and visual modalities with ease and speed. However, how the brain learns multisensory categories remains elusive. The present study used functional magnetic resonance imaging to investigate, for the first time, the neural mechanisms underpinning multisensory information-integration (II) category learning. A sensory-modality-general network, including the left insula, right inferior frontal gyrus (IFG), supplementary motor area, left precentral gyrus, bilateral parietal cortex, and right caudate and globus pallidus, was recruited for II categorization, regardless of whether the information came from a single modality or from multiple modalities. Putamen activity was higher in correct categorization than incorrect categorization. Critically, the left IFG and left body and tail of the caudate were activated in multisensory II categorization but not in unisensory II categorization, which suggests this network plays a specific role in integrating multisensory information during category learning. The present results extend our understanding of the role of the left IFG in multisensory processing from the linguistic domain to a broader role in audiovisual learning.