2D DNA lattice arrays assembled from DNA dumbbell tiles using poly(A-T)-rich stems
2D DNA lattice arrays assembled from DNA dumbbell tiles using poly(A-T)-rich stems
复制标题
使用富含聚 (A-T) 的茎由 DNA 哑铃片组装而成的 2D DNA 晶格阵列
DOI：
10.1039/c9nr07911d
复制
发表时间：
2019-12-14
期刊：
影响因子：
6.7
通讯作者：
Xiao, Shou-Jun
中科院分区：
文献类型：
--
作者：
Ali, Mashooq;Afshan, Noshin;Xiao, Shou-Jun
富含Poly（A-T）的序列已被用作DNA哑铃瓦片的茎，用于在微酸性溶液中构建单晶2D DNA晶格阵列。这些阵列显示出更高的稳定性和更好的组织晶格结构比那些组装的DNA哑铃瓦片与随机排序的茎在微碱性环境中。DNA纳米技术可能为研究特定序列DNA双链体的力学性质提供了一个有用的平台。
Poly(A-T)-rich sequences have been applied as stems of DNA dumbbell tiles for construction of single crystalline 2D DNA lattice arrays in slightly acidic solutions. These arrays show much higher stability and better organised crystalline lattice structures than those assembled from DNA dumbbell tiles with randomly sequenced stems in slightly alkaline environments. DNA nano-technology probably provides a useful platform to study the mechanical properties of DNA duplexes with specific sequences.