Prevalence, clinical and ultrasonographic characteristics of thyroid incidentalomas
Prevalence, clinical and ultrasonographic characteristics of thyroid incidentalomas
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DOI：
10.1089/105072504322783812
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发表时间：
2004-01-01
期刊：
影响因子：
6.6
通讯作者：
Kim, KW
中科院分区：
文献类型：
--
作者：
Kang, HW;No, JH;Kim, KW
高分辨率超声（US）使无症状甲状腺小结节的检测成为可能。甲状腺偶发瘤已经造成了一个临床困境，如何妥善处理这样的偶然发现。我们调查了< 1.5 cm甲状腺结节的患病率、临床和超声特征以及偶然发现的良性和恶性甲状腺结节的最佳诊断方法。对1999年1月至2000年12月在韩国首尔三星医疗中心就诊的1475例患者进行回顾性分析。甲状腺偶发瘤的患病率为13.4%。甲状腺偶发瘤恶性率为28.8%。良、恶性偶发瘤在年龄、结节大小、数目、甲状腺功能、99m Tc甲状腺显像等方面差异无统计学意义。甲状腺偶发瘤的超声表现为实性回声、边界不规则、钙化，对甲状腺偶发瘤的恶性诊断有意义（P < 0.05）。恶性偶发瘤多为低分期。总之，隐匿性甲状腺癌是一个相当常见的发现。甲状腺良、恶性结节的临床及实验室指标无显著性差异
High-resolution ultrasonography (US) has made possible the detection of asymptomatic small thyroid nodules. Thyroid incidentalomas have created a clinical dilemma as to how to properly manage such incidental findings. We investigated the prevalence, the clinical and US characteristics, and optimal diagnostic approach to incidentally detected benign and malignant thyroid nodules < 1.5 cm. Retrospective review was done on 1475 patients who had visited Samsung Medical Center, Soul Korea from January 1999 to December 2000. The prevalence of thyroid incidentalomas was 13.4%. The malignancy rate within thyroid incidentalomas was 28.8%. There were no significant differences in age, nodule size and number, thyroid function test, and Tc-99m thyroid scan between benign and malignant incidentalomas. US characteristics of solid echostructure, irregular margin, and calcification showed meaningful diagnostic value in detecting malignancy in thyroid incidentalomas (p < 0.05). Most malignant incidentalomas were low stage. In conclusion, occult thyroid cancers are a fairly common finding. There were no significant differences in clinical and laboratory parameters between benign and malignant thyroid nodules