Ultrashort TE evaluation of the osteochondral junction in vivo: a feasibility study
Ultrashort TE evaluation of the osteochondral junction in vivo: a feasibility study
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DOI：
10.1259/bjr.20150493
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发表时间：
2016-01-01
影响因子：
2.6
通讯作者：
Toms, Andoni P.
中科院分区：
文献类型：
--
作者：
Mackay, James W.;Low, Samantha B. L.;Toms, Andoni P.
目的：为了确定是否差异在两个不同年龄组的骨软骨连接（OCJ）可以检测到与超短时间回波（UTE）MRI in vivo.Methods：10名健康对照组年龄20-30岁（组1）和10名患者年龄40-50岁的膝关节疼痛，但没有证据骨关节炎（OA）（组2）进行了3-T MRI的膝盖使用二维UTE序列。评价胫骨内侧/胫骨外侧（MT/LT）OCJ处是否存在高信号强度（SI）线。在MT OCJ和LT OCJ处创建感兴趣区（ROI）。通过使用平均头尾SI轮廓测量峰值OCJ SI，然后除以背景ROI的平均SI来计算峰值OCJ SI比，以在研究之间进行标准化。使用卡方（2）和Mann-Whitney U检验比较各组。结果：在两个MT（P
Objective: To determine whether differences in the osteochondral junction (OCJ) in two different age groups could be detected with ultrashort time-to-echo (UTE) MRI in vivo.Methods: 10 healthy controls aged 20-30 years (Group 1) and 10 patients aged 40-50 years with knee pain but no evidence of osteoarthritis (OA) (Group 2) underwent 3-T MRI of the knee using a two-dimensional UTE sequence. Evaluation of the presence/absence of a high-signal-intensity (SI) line at the medial tibial/lateral tibial (MT/LT) OCJ was performed. Regions of interest (ROI) were created at the MT OCJ and LT OCJ. The peak OCJ SI ratio was calculated by measuring peak OCJ SI using averaged craniocaudal SI profiling, then dividing by the mean SI of a background ROI to standardize between studies. Groups were compared using chi(2) and Mann-Whitney U tests.Results: A high SI line was present in significantly more Group 1 subjects at both MT (p