Selectively-Permeable Ultrathin Film Composite Membranes Based on Molecularly-Imprinted Polymers
Selectively-Permeable Ultrathin Film Composite Membranes Based on Molecularly-Imprinted Polymers
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基于分子印迹聚合物的选择性渗透超薄膜复合膜
DOI：
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发表时间：
1998
期刊：
影响因子：
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通讯作者：
C. Martin
中科院分区：
文献类型：
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作者：
Jae;Patrick Anderson;J. Qian;C. Martin
基于膜的化学分离构成了一个新兴的研究领域和工业技术。目标是开发选择性传输特定目标分子并拒绝（或以低得多的速率传输）进料溶液中可能存在的其他分子的膜。本文描述了一种制备用于药物或生物医学分离的高选择性复合膜的新方法。这种方法需要在微孔支撑物表面上进行“分子印迹聚合物薄膜”的光聚合，形成新型超薄膜复合膜。制备了基于印迹在支气管扩张剂茶碱上的聚合物的复合膜。研究了茶碱在这些超薄膜复合材料上的传输速率和选择性。
Membrane-based chemical separations constitute an emerging research area and industrial technology. The objective is to develop membranes that selectively transport a particular target molecule and reject (or transport at much lower rates) other molecules that might be present in the feed solution. This paper describes a new approach for preparing highly selective composite membranes for pharmaceutical or biomedical separations. This approach entails photopolymerization of a “molecularly-imprinted polymer film” across the surface of a microporous support to form a new type of ultrathin film composite membrane. Composite membranes based on polymers that were imprinted on the bronchodilator theophylline were prepared. The rate and selectivity of theophylline transport across these ultrathin film composites were investigated.