A new quassinoid from Castela texana
A new quassinoid from Castela texana
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DOI：
10.1021/np960013j
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发表时间：
1996-01-01
影响因子：
5.1
通讯作者：
Walker, LA
中科院分区：
文献类型：
--
作者：
Dou, JH;McChesney, JD;Walker, LA
从得克萨斯堡中分得一个新的苦木素类化合物11-O-反式-对香豆酰苦杏仁甙（1），经波谱分析确定其结构。化合物1是第一个从自然界中分离出来的香豆酰类苦木素衍生物。已知化合物苦杏仁苷（2），chaparrinone，chaparrin，glaucarubolone，holacanthone和15-O-β-D-吡喃葡萄糖基glaucarubol也被分离出来。所有分离的化合物进行了测试，其细胞毒性和抗原动物活性。
A new quassinoid, 11-O-trans-p-coumaroyl amarolide (1) was isolated from Castela texana, and the structure was elucidated by spectroscopic analysis. Compound 1 is the first-coumaroyl quassinoid derivative to have been isolated from nature. The known compounds amarolide (2), chaparrinone, chaparrin, glaucarubolone, holacanthone, and 15-O-beta-D-glucopyranosyl glaucarubol were also isolated. All isolated compounds were tested for their cytotoxicity and antiprotozoal activities.