Role of disease severity, illness perceptions, and mood on quality of life in muscle disease
Role of disease severity, illness perceptions, and mood on quality of life in muscle disease
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DOI：
10.1002/mus.23320
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发表时间：
2012-09-01
期刊：
影响因子：
3.4
通讯作者：
Jackson, Carlayne E.
中科院分区：
文献类型：
--
作者：
Rose, Michael R.;Sadjadi, Reza;Jackson, Carlayne E.
前言：本研究的目的是描述肌肉疾病对生活质量的影响，并探讨疾病严重程度、情绪和疾病知觉对这些患者生活质量的影响。方法：对肌肉疾病患者进行QOL(个体化神经肌肉QOL和SF-36)、疾病严重程度(健康评估问卷)、心境(医院焦虑抑郁量表)和疾病知觉(疾病知觉问卷)的有效问卷调查。结果：共收到302份问卷，回收率为75%。生活质量下降，特别是在生理领域，但心理领域也受到影响。疾病的严重程度是影响生活质量的主要生理因素，但情绪和疾病感知起到了一定作用。相反，情绪和疾病感知是影响QOL心理领域的主要决定因素。结论：由于情绪和疾病知觉可以解释肌肉疾病患者生活质量的显著差异，因此有可能设计心理社会干预措施来改善肌肉疾病患者的生活质量。肌肉神经46：351359,2012年
Introduction: The aim of this study was to describe the effect of muscle disease upon QoL and to explore the influence of disease severity, mood, and illness perception on the QoL of these patients. Methods: Validated questionnaires assessing QoL (Individualized Neuromuscular QoL and SF-36), disease severity (Health Assessment Questionnaire), mood (Hospital Anxiety and Depression Scale) and illness perception (Illness Perception Questionnaire) were sent to adults with muscle disease. Results: We received 302 responses (return rate 75%). QoL was reduced, particularly for physical domains, but psychological domains were also affected. Disease severity was the main determinant for the physical domains of QoL, but mood and illness perception played a part. Conversely, mood and illness perception were the main determinants for the psychological domains of QoL. Conclusions: Because mood and illness perception explain significant variance in QoL in muscle disease, there is scope for devising psychosocial interventions that may improve QoL for those with muscle disease. Muscle Nerve 46: 351359, 2012