Dammarane- and taraxastane-type triterpenoids from Saussurea oligantha Franch

Dammarane- and taraxastane-type triterpenoids from Saussurea oligantha Franch
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DOI:
10.1080/10286020801966583
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发表时间:
2008-01-01
影响因子:
1.7
通讯作者:
Shi, Yan-Ping
Shi, Yan-Ping
中科院分区:
医学4区
文献类型:
--
作者:
Li, Xue-Hu;Qi, Huan-Yang;Shi, Yan-Ping

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A new dammarane triterpenoid oliganthas A (1) and a new taraxastane triterpenoid oliganthas B (2), as well as five known taraxastane triterpenoids, ptiloepoxide (3), taraxast-20(30)ene-3,21-diol (4), 22-oxo-20-taraxasten-3-ol (5), taraxast-20-ene-3,30-diol (6), and taraxastane-3,20-diol (7), were isolated from the whole plant of Saussurea oligantha Franch. Their structures were elucidated by a series of spectroscopic methods. These compounds, especially taraxastanes 2, 5, and 6, exhibited significant antibacterial activity against Actinomyces viscosus ATCC27044.