DISCHARGE PATTERNS OF CAT PRIMARY AUDITORY FIBERS WITH ELECTRICAL-STIMULATION OF THE COCHLEA
DISCHARGE PATTERNS OF CAT PRIMARY AUDITORY FIBERS WITH ELECTRICAL-STIMULATION OF THE COCHLEA
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DOI：
10.1016/0378-5955(84)90094-7
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发表时间：
1984-01-01
期刊：
影响因子：
2.8
通讯作者：
KLINKE, R
中科院分区：
文献类型：
--
作者：
HARTMANN, R;TOPP, G;KLINKE, R
通过圆窗电极电刺激完整和破坏的猫耳蜗。完整的耳蜗提供了有关纤维特性与声刺激的信息。对于正弦电流，用于同步的阈值为4-68 μ A rms [均方根]。耳蜗纤维的特征频率和它们在完整耳蜗中的起源位置是无关的。这表明电流分布很大。对电刺激的反应的锁相比对声刺激的反应强得多。被破坏的耳蜗没有自发活动，并显示出更强的锁相。使用每相0.2 ms双相脉冲刺激获得的阈值为60-350 μ App。动作电位以低至0.3 ms的潜伏期释放。神经元对任何电刺激的反应与对相应的声刺激的反应有很大不同。前庭纤维容易被电刺激激活。
Intact and destroyed cat cochleae were electrically stimulated through round window electrodes. Intact cochleae provided information about fiber properties with acoustic stimuli. With sinusoidal currents threshholds for synchronization were 4-68 .mu.A rms [root mean square]. Thresholds were independent of the fiber''s characteristic frequencies and thus of their places of origin in the intact cochleae. This shows large current spread. Phase locking of the responses to electric stimulation was much stronger than it was to acoustic stimulation. Destroyed cochleae had no spontaneous activity and showed even stronger phase-locking. Thresholds obtained using 0.2 ms per phase biphasic pulse stimuli were 60-350 .mu.App. Action potentials were released with as little as 0.3 ms latency. The neuronal responses to any electrical stimulus differed considerably from the responses to corresponding acoustic stimuli. Vestibular fibers were easily activated by electrical stimulation.