Comparison of a Rapid Antigen Test with Nucleic Acid Testing during Cocirculation of Pandemic Influenza A/H1N1 2009 and Seasonal Influenza A/H3N2
Comparison of a Rapid Antigen Test with Nucleic Acid Testing during Cocirculation of Pandemic Influenza A/H1N1 2009 and Seasonal Influenza A/H3N2
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DOI：
10.1128/jcm.01465-09
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发表时间：
2010-01-01
影响因子：
9.4
通讯作者：
Dwyer, Dominic E.
中科院分区：
文献类型：
--
作者：
Kok, Jen;Blyth, Christopher C.;Dwyer, Dominic E.
流感的快速诊断对于优化临床管理至关重要。与季节性甲型流感亚型相比，快速抗原检测检测大流行性甲型流感/H1N1 2009 病毒的敏感性较低（53.4% 对比 74.2%，P < 0.001）。当快速抗原检测呈阴性时，应使用核酸检测来检测大流行性流感病毒。
The rapid diagnosis of influenza is critical in optimizing clinical management. Rapid antigen tests have decreased sensitivity in detecting pandemic influenza A/H1N1 2009 virus compared to seasonal influenza A subtypes (53.4% versus 74.2%, P < 0.001). Nucleic acid tests should be used to detect pandemic influenza virus when rapid antigen tests are negative.