DNA sequence mapping by fluorescence in situ hybridization
DNA sequence mapping by fluorescence in situ hybridization
复制标题
通过荧光原位杂交绘制 DNA 序列图
DOI:
10.1002/em.2850180410
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发表时间:
1991
影响因子:
2.8
通讯作者:
B. Trask
中科院分区:
文献类型:
--
作者:
B. Brandriff;L. Gordon;B. Trask
Various types of DNA probes, such as total genomic DNA, repetitive sequences, unique sequences, and composites of chromosome‐specific DNA probes, can be used with fluorescence in situ hybridization (FISH) techniques to address research questions having to do with localization, mapping, and distribution of DNA in situ. FISH involves the formation of a heteroduplex between such DNA probes and chromatin targets on a microscope slide, which can be visualized with fluorescent reporter molecules. Three chromatin targets—metaphase chromosomes, somatic interphases, and zygote interphases‐offer increasingly extended states of chromatin which can be strategically selected, individually or in combination, to address specific research questions of interest.
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DOI:
10.1073/pnas.83.9.2934
发表时间:
1986-05-01
影响因子:
11.1
作者:
PINKEL, D;STRAUME, T;GRAY, JW
通讯作者:
GRAY, JW
影响因子:
4.4
作者:
Trask,B;Pinkel,D;vandenEngh,G
通讯作者:
vandenEngh,G
影响因子:
9.8
作者:
B. Trask;H. Massa;Sue Kenwrickt;Jane Gitschiert
通讯作者:
B. Trask;H. Massa;Sue Kenwrickt;Jane Gitschiert
影响因子:
56.9
作者:
LICHTER, P;TANG, CJC;WARD, DC
通讯作者:
WARD, DC
影响因子:
4.4
作者:
Jabs,EW;Warren,AC;Taylor,EW;Colyer,CR;Meyers,DA;Antonarakis,SE
通讯作者:
Antonarakis,SE