Exposure to Air Pollution Increases the Incidence of Hypertension and Diabetes in Black Women Living in Los Angeles
Exposure to Air Pollution Increases the Incidence of Hypertension and Diabetes in Black Women Living in Los Angeles
复制标题
DOI：
10.1111/jch.12000
复制
发表时间：
2012-11-01
影响因子：
2.8
通讯作者：
Bloch, Michael J.
中科院分区：
文献类型：
--
作者：
Basile, Jan N.;Bloch, Michael J.
虽然肯定不是确定的，这份报告是第一个强有力的迹象表明，以前观察到的污染暴露和CV事件之间的关联可能至少部分是由高血压事件的风险增加介导的。虽然这里看到的关联程度并不大，但考虑到高血压的绝对发病率和美国大多数大城市普遍暴露于空气污染，即使高血压相对风险增加15%，也可能代表高血压发病病例的绝对数量非常大。我们应该记住，这项研究确实有很大的局限性。但是，这些数据应该鼓励其他群体尝试在其他人口群体和其他地理位置复制这些发现。未来的研究也将受益于直接测量血压作为方法的一部分，而不是自我报告的高血压诊断。
IMPLICATIONS AND CONCLUSIONS While certainly not definitive, this report is the first strong indication that the previously observed association between pollution exposure and CV events may at least in part be mediated by an increased risk of incident hypertension. While the magnitude of the association seen here was not large, given the absolute incidence of hypertension and the widespread exposure to air pollution present in most US metropolitan cities, even a 15% increase in the relative risk of hypertension may represent a very substantial absolute number of incident hypertension cases. We should keep in mind that this study does have significant limitations. But, these data should encourage other groups to attempt to replicate these findings in other demographic groups and other geographic locations. Future studies would also benefit from having blood pressure measured directly as part of the methodology rather than a diagnosis of hypertension being self-reported.