Distinct unimodal and multimodal regions for word processing in the left temporal cortex
Distinct unimodal and multimodal regions for word processing in the left temporal cortex
复制标题
DOI：
10.1016/j.neuroimage.2004.07.052
复制
发表时间：
2004-12-01
期刊：
影响因子：
5.7
通讯作者：
Dehaene, S
中科院分区：
文献类型：
--
作者：
Cohen, L;Jobert, A;Dehaene, S
左颞叶中的文字识别回路是如何组织的？我们使用功能性磁共振成像（fMRI）来解剖皮质文字处理电路，使用三个诊断标准：一个区域（1）以单一模态对词语作出反应的能力（2）以自上而下的方式调节其响应，作为任务的字形或音素强调的函数，以及（3）响应于目标词在相同感觉模态内或跨不同模态的有意识重复而显示重复抑制。结果澄清了视觉和听觉文字处理流的组织。特别是，视觉词形区（VWFA）在左枕颞沟出现严格的视觉单峰区。然而，它与第二个多模态的外侧颞下区（lateral interferotemporal area，LIMA）相邻。在过去的工作中，这两个领域可能会混淆。我们的研究结果还表明，在听觉流，听觉词形区，位于左前上级颞沟的VWFA可能的同系物。(C)2004年爱思唯尔公司All rights reserved.
How are word recognition circuits organized in the left temporal lobe? We used functional magnetic resonance imaging (fMRI) to dissect cortical word-processing circuits using three diagnostic criteria: the capacity of an area (1) to respond to words in a single modality (visual or auditory) or in both modalities, (2) to modulate its response in a top-down manner as a function of the graphemic or phonemic emphasis of the task, and (3) to show repetition suppression in response to the conscious repetition of the target word within the same sensory modality or across different modalities. The results clarify the organization of visual and auditory word-processing streams. In particular, the visual word form area (VWFA) in the left occipitotemporal sulcus appears strictly as a visual unimodal area. It is, however, bordered by a second lateral inferotemporal area which is multimodal [lateral inferotemporal multimodal area (LIMA)]. Both areas might have been confounded in past work. Our results also suggest a possible homolog of the VWFA in the auditory stream, the auditory word form area, located in the left anterior superior temporal sulcus. (C) 2004 Elsevier Inc. All rights reserved.