The risk factors associated with MERS-CoV patient fatality: A global survey
The risk factors associated with MERS-CoV patient fatality: A global survey
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DOI：
10.1016/j.diagmicrobio.2019.114876
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发表时间：
2020-03-01
影响因子：
2.9
通讯作者：
Mohebbi, Iraj
中科院分区：
文献类型：
--
作者：
Ahmadzadeh, Jamal;Mobaraki, Kazhal;Mohebbi, Iraj
通过分析 2012 年 9 月 23 日至 2018 年 6 月 18 日的世卫组织数据，确定了与中东呼吸综合征冠状病毒 (MERS-CoV) 感染结果相关的危险因素。在 2220 例报告病例中，分析了 1408 例病例，其中包括 451 例 MERS-CoV 死亡病例。病死率为 32%（95% CI：29.4-34.5）。与 0.30 岁的 MERS 患者相比，30 岁以上患者的死亡比值比调整后估计值为 2.38 [95% CI：1.75-3.22]。与非沙特患者相比，沙特患者的该指数为 1.43 [95% CI：1.06-1.92]；与没有合并症的患者相比，有合并症的患者为 1.76 [95% CI：1.39-2.22]；与患有以下疾病的患者相比，在过去 14 天内与骆驼有过密切接触的患者为 0.58 [95% CI: 0.44-0.75]，对于出现症状并入院超过 14 天的患者为 0.42 [95% CI: 031-0.57]。
Risk factors associated with Middle East respiratory syndrome coronavirus (MERS-CoV) infection outcome were established by analyses of WHO data from September 23, 2012 to 18 June 2018. Of the 2220 reported cases, 1408 cases, including 451 MERS-CoV deaths, were analyzed. The case fatality rate was 32% (95% CI: 29.4-34.5). Compared to MERS patients .30 years old, those with >30 years had the adjusted odds ratio estimate for death of 2.38 [95% CI: 1.75-3.22]. This index was 1.43 [95% CI: 1.06-1.92] for Saudi patients in comparison to non-Saudi; 1.76 [95% CI: 1.39-2.22] for patient with comorbidity in comparison to those without comorbidity; 0.58 [95% CI: 0.44-0.75] for those who had close contact to a camel in the past 14 days and 0.42 [95% CI: 031-0.57] for patients with >14 days with onset of signs and hospital admission compared to patients with