Fluid surface tension evaluation using capillary wave measurement with optical coherence tomography
Fluid surface tension evaluation using capillary wave measurement with optical coherence tomography
复制标题
DOI：
10.1063/1.5143935
复制
发表时间：
2020-05-01
期刊：
影响因子：
1.6
通讯作者：
Urban, Matthew W.
中科院分区：
文献类型：
--
作者：
Liu, Hsiao-Chuan;Kijanka, Piotr;Urban, Matthew W.
生物流体的表面张力是一个重要的参数，因为流体的机械性质与血液疾病和其他病理生理密切相关。毛细波与流体力学性质有关。在这里，我们提出了一种方法，利用声辐射力（ARF）来产生传播波和光学相干断层扫描（OCT）来测量波动。基于毛细波的色散关系，本研究中的ARF-OCT方法能够评估流体、水和猪全血的表面张力。二维傅里叶变换被用来分解的波动图像的频率分量，以获得一个k空间表示和估计的波相速度。从实验结果中获得了毛细管波的相速度，并与理论计算进行了比较。根据实验结果测定了水和猪全血的表面张力。我们首先报告，毛细管波测量OCT可以是一个新的有前途的方式来测量流体的表面张力。所提出的方法可用于区分实际的病理液体或血液从健康受试者，并作为生物标志物在未来的生物医学应用。
The surface tension of biological fluids is an important parameter because the mechanical properties of fluids are closely linked with hematological diseases and other pathophysiologies. Capillary waves are associated with fluid mechanical properties. Here, we propose a method that utilizes the acoustic radiation force (ARF) to generate propagating waves and optical coherence tomography (OCT) to measure the wave motion. This ARF-OCT method is capable of evaluating the surface tension of fluids, water and porcine whole blood in this study, based on the dispersion relation of capillary waves. Two-dimensional Fourier transforms were used to decompose frequency components of wave motion images to obtain a k-space representation and estimate the wave phase velocity. The phase velocity of capillary waves was obtained from the experimental results and compared to theoretical calculations. The surface tensions of water and porcine whole blood were determined from the experimental results. We first report that capillary waves measured with OCT can be a new promising modality for measuring the surface tension of fluids. The proposed method could be used to differentiate actual pathologic fluids or blood from those taken from healthy subjects and as a biomarker in future biomedical applications.